Novel Synthesis Method of Hydroxyapatite Whiskers by Hydrolysis of alpha‐Tricalcium Phosphate in Mixtures of Water and Organic Solvent

Abstract

A novel and simple nonhydrothermal method was developed for synthesizing hydroxyapatite whiskers under mild conditions. Hydroxyapatite whiskers were synthesized by the hydrolysis of ␣-tricalcium phosphate at 80°C and atmospheric pressure. The effect of aliphatic alcohols on the transformation of ␣-tricalcium phosphate to hydroxyapatite in water-alcohol systems was examined. When the hydroxyapatite was characterized by XRD and TEM observation, its morphology and size were found to vary with the specific alcohol used during hydrolysis. The effect of reaction time on hydrolysis of ␣-tricalcium phosphate to hydroxyapatite also was studied.

Synthesis and evaluation of porous hydroxyapatite prepared by hydrothermal treatment and subsequent sintering method

“…12) A powder of a-tricalcium phosphate (a-TCP: Taihei Chemical Industrial Co.) was used for the starting powder. 10 g of a-TCP was stirred in 200 ml of 1-Octanol (Wako Pure Chemical Industries) at 70°C, for 48 h. The solution during reaction time was kept pH11 by 0.1N-NH 4 OH.…”

Regulation of the protein-loading capacity of hydroxyapatite by mercaptosuccinic acid modification

“…bone absorption by periodontal disease), excellent mechanical properties are not crucial characteristics for the materials. Unique morphology, such as granules or particles, is used for this purpose [6][7][8][9]. In addition, materials that possess osteoinductivity might be effective at shortening the bone regeneration period.…”

Transmission Electron Microscopic Study on the Migration of Ca Ions in Ca-Deficient Hydroxyapatite during Thermal Decomposition

“…The details for the synthesis of the Cadef HAp was referred to our previous paper. 10) Substitutions of Ca ions in Cadef HAp by Sr ion were carried out by hydrothermal treatment. 0.5 mmol of Cadef HAp and 50 cm 3 of 0.5 mol/dm 3 Sr(NO 3 ) 2 were mixed.…”