Novel treatment of Hori′s nevus: A combination of fractional nonablative 2,940-nm Er:YAG and low-fluence 1,064-nm Q-switched Nd:YAG laser

Abstract

Objective:To demonstrate a combination laser therapy to treat Hori's nevus.Design:A prospective study.Setting:A Singapore-based clinic.Participants:Five female patients, aged 30-46 years, with bilateral malar Hori's nevus.Measurements:Photographs were taken before treatment and 1 month after laser treatment was completed. These were graded by three independent physicians. The patients were also asked to grade their treatment response subjectively. They were followed up for a total of 3 months after laser treatment to monitor recurrence.Materials and Methods:The fractional nonablative 2,940-nm Er:YAG laser with a fluence of 0.7 J/cm2, spot size 12 mm, and frequency 15 Hz was used to perform a full-face single-pass treatment. Subsequently, a second pass and third pass over Hori's nevi were done bilaterally till the clinical endpoint of skin whitening. The 1,064-nm Q-switched (QS) Nd:YAG at a fluence of 2.0 J/cm2, frequency 2 Hz, and 4-mm spot size was used to deliver multiple passes over Hori's nevus till erythema with mild petechiae appeared. We repeated the treatment once a week for 3 more consecutive weeks.Results:All five patients had above 80% improvement in their pigmentation and two (skin type III) achieved complete 100% clearance. Based on the patients’ subjective assessments, all five of them expressed satisfaction and felt that their pigmentation had improved. There were no complications noted.Conclusion:The fractional nonablative 2940 nm Er:YAG laser and Q-switched 1064nm laser Nd:YAG combination is an effective and safe treatment for Hori's nevus.

Therapeutic options for management of Hori's nevus: A systematic review

“…All the patients expressed satisfaction and no adverse effects were observed during the follow‐up. As the two lasers work on different targets synergistically, the investigators could choose lower fluence for each laser type, which can reduce the chance of complications (Tian, ).…”

“…Similar comparable efficacy was seen (excellent response in all participants after three or more sessions) in case of combined Er:YAG + Nd:YAG laser treatment, and the advantage of this combination of lasers was that it acted synergistically and no adverse event of the procedure was seen (including dyschromia). The synergistic action of both the lasers allowed to apply low fluence of both resulting in less adverse events (Tian, ).…”

Facial Hyperpigmentation in Skin of Color: Special Considerations and Treatment

“…Although many treatment modalities have been tried, the most successful means of removal include the use of QS lasers; in individuals with skin of color, use of the longer wavelength Nd:YAG is safest [80][81][82][83][84][85][86].…”

The Treatment of Hori's Nevus by New Combination Treatment without Side Effects: Dr. Hoon Hur's Golden Parameter Therapy and Dr. Hoon Hur's Optimal Melanocytic Suicide-2 Parameter Therapy

“…The treatment of Hori's nevus is necessary because of cosmetic concerns. But the treatment of Hori's nevus without side effects such as purpura, crust, Postinflammatory Hyperpigmentation (PIH), scarring and recurrences is very difficult [4][5][6][7]. In this paper, we present the new combination treatment of Hori's nevus using Dr. Hoon Hur's Golden Parameter with a high fluence 1064nm Q-switched Nd:YAG laser and Dr. Hoon Hur's Optimal Melanocytic Suicide-2 Parameter with a high fluence 1064nm Q-switched Nd:YAG laser without side effects and recurrences.…”