Novos rumos da epistemologia social

Ruivo, Leonardo Alexandre de Souza; Cichosk, Luiz; Santos, Breno Ricardo Guimarães

doi:10.22350/9786559176908

Cited by 1 publication

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“…--Can take up cystine when expressed at the plasma membrane in vitro, which is consistent with its proposed biological role and association with the disease cystinosis [370]. Acts as a cystine/H + symporter at a 1:1 stiochiometry [595].…”

Section: Slc66 Lysosomal Amino Acid Transportersmentioning

confidence: 54%

THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Transporters

Alexander

Kelly

Mathie

et al. 2021

British J Pharmacology

146

149

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The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of nearly 1900 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (https://www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes over 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point‐in‐time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/bph.15543. Transporters are one of the six major pharmacological targets into which the Guide is divided, with the others being: G protein‐coupled receptors, ion channels, nuclear hormone receptors, catalytic receptors and enzymes. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid‐2021, and supersedes data presented in the 2019/20, 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC‐IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.

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Section: Slc66 Lysosomal Amino Acid Transportersmentioning

confidence: 54%