“…By exploring the subjective experiences of MSM in their navigation of PrEP, these authors have identified, mostly through in-depth interviews or in focus groups, numerous and varied motivations for using (or not using) PrEP that call into question the usefulness of biomedical approaches to PrEP implementation that de-emphasise psychosocial phenomena. In many cases, the motivations identified in these studies have stemmed from powerful affective experiences, such as being freed from sometimes decades-long, often cyclical anxiety about HIV infection [ 37 , 38 , 54 , 55 ]; feeling empowered, able to make one’s own informed choices, in control or autonomous [ 37 , 56 ]; and feeling less fear and shame in relation to pre-existing high-risk sexual behaviours alongside greater sexual satisfaction and intimacy [ 57 , 58 ]. The qualitative literature also reports motivations related to fearing or experiencing PrEP-related stigma, such as beliefs that PrEP is only for those who are highly promiscuous [ 56 , 59 ]; being labelled a “Truvada whore” (or similar) in lesbian, gay, bisexual, transgender, intersex and other gender diverse (LGBTI+) media, or by peers or even friends [ 60 ]; encountering provider-level stigma, including judgemental behaviour about the decision to use PrEP [ 35 ]; or experiencing, as a PrEP user or non-user, increased pressure to engage in condomless anal intercourse [ 37 , 58 , 61 ].…”