Various estimates of the even-odd effect of the mass shell of atomic nuclei are considered. Based on the experimental mass values of the Ca, Sn, and Pb isotopes, the dependence of the energy gap on the neutron number is traced and the relationship of this characteristic to the properties of external neutron subshells is shown. In nuclei with closed proton shells, effects directly related to neutron pairing and effects of nucleon shells are discussed.Key words nucleon interaction, models of atomic nuclei, nucleon pairing in atomic nuclei