Abstract. Core-collapse supernovae are the first polluters of heavy elements in the galactic history. As such, it is important to study the nuclear compositions of their ejecta, and understand their dependence on the progenitor structure (e.g., mass, compactness, metallicity). Here, we present a detailed nucleosynthesis study based on two long-term, two-dimensional core-collapse supernova simulations of a 11.2 M and a 17.0 M star. We find that in both models nuclei well beyond the iron group (up to Z ≈ 44) can be produced, and discuss in detail also the nucleosynthesis of the p-nuclei 92,94 Mo and 96,98 Ru. While we observe the production of 92 Mo and 94 Mo in slightly neutron-rich conditions in both simulations, 96,98 Ru can only be produced efficiently via the νp-process. Furthermore, the production of Ru in the νp-process heavily depends on the presence of very proton-rich material in the ejecta. This disentanglement of production mechanisms has interesting consequences when comparing to the abundance ratios between these isotopes in the solar system and in presolar grains.