Nucleotide-rich yeast extract fed to broiler chickens challenged with Eimeria: impact on growth performance, jejunal histomorphology, immune system, and apparent retention of dietary components and caloric efficiency

Leung, H.; Patterson, Rob; Barta, John R.; Karrow, Neil A.; Kiarie, E.

doi:10.3382/ps/pez213

Cited by 19 publications

(41 citation statements)

References 37 publications

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“…The failure of parasitized animals to grow is partially due to loss of appetite and nutrient malabsorption (84,86,(92)(93)(94). Structural and functional damages to the small intestine are indicated by the histomorphology, digestive enzymes, nutrients transporters, and nutrient retention in our model (84,86,87). Moreover, E. acervulina and E. maxima infection down regulates expression of digestive enzymes and nutrient transporters (84,87,(93)(94)(95).…”

Section: Utility Of Feed Enzymes and Yeast Derivatives In Mitigating mentioning

confidence: 92%

“…Eimeria destruction of intestinal lining results in poor growth performance, loose excreta and death in extreme cases (5,14). The failure of parasitized animals to grow is partially due to loss of appetite and nutrient malabsorption (84,86,(92)(93)(94). Structural and functional damages to the small intestine are indicated by the histomorphology, digestive enzymes, nutrients transporters, and nutrient retention in our model (84,86,87).…”

Section: Utility Of Feed Enzymes and Yeast Derivatives In Mitigating mentioning

confidence: 95%

“…Our laboratory has developed a model to examine effects of coccidiosis on digestion and absorptive capacities and subsequent effects on GIT ecology. The rationale is to use this infection model to test dietary strategies during acute phase and recovery phases (84)(85)(86)(87)(88). The general approach is to challenge sub-samples of birds in a pen with high dose (100,000 E. acervullina and 60,000 E. maxima sporulated oocysts) to generate macroscopic lesions and the rest of birds with a low dose (25,000 E. acervulina and 5,000 E. maxima sporulated oocysts) in order to examine the consequences of altered nutrient digestion and absorption.…”

Section: Utility Of Feed Enzymes and Yeast Derivatives In Mitigating mentioning

confidence: 99%

“…Coccidiosis effectively reduces nutrients digestion and absorption linked to anorexia in concurrence with morphological and functional intestinal damage (Figure 2) (84,86,87). Increased mucogenesis and enterocyte turnover (84), as well as postabsorptive metabolic changes and immune system activation, likely influence nutrient needs of broilers (9).…”

Section: Utility Of Feed Enzymes In Modulating Coccidiosis In Broilersmentioning

confidence: 99%

“…However, it has been shown that coccidiosis markedly increased maintenance energy requirement. For example, Leung et al (86), observed a 16% decrease in energy allocated to body weight gain (measured in caloric efficiency) in a 35-day old bird challenged with E. acervulina and E. Maxima at day 10 of age. The energy needed for immunity development was 5% in healthy birds compared to 28% for coccidiosis challenged birds and this cost became disproportionately elevated as the birds became heavier aged (97).…”

Section: Utility Of Feed Enzymes In Modulating Coccidiosis In Broilersmentioning

confidence: 99%

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Utility of Feed Enzymes and Yeast Derivatives in Ameliorating Deleterious Effects of Coccidiosis on Intestinal Health and Function in Broiler Chickens

et al. 2019

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Section: Utility Of Feed Enzymes and Yeast Derivatives In Mitigating mentioning

confidence: 92%

Section: Utility Of Feed Enzymes and Yeast Derivatives In Mitigating mentioning

confidence: 95%

Section: Utility Of Feed Enzymes and Yeast Derivatives In Mitigating mentioning

confidence: 99%

Section: Utility Of Feed Enzymes In Modulating Coccidiosis In Broilersmentioning

confidence: 99%

Section: Utility Of Feed Enzymes In Modulating Coccidiosis In Broilersmentioning

confidence: 99%

See 3 more Smart Citations

Utility of Feed Enzymes and Yeast Derivatives in Ameliorating Deleterious Effects of Coccidiosis on Intestinal Health and Function in Broiler Chickens

et al. 2019

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Effects of yeast hydrolysate on growth performance, serum parameters, carcass traits, meat quality and antioxidant status of broiler chickens

Wang

Cheng

et al. 2021

J Sci Food Agric

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BACKGROUND Yeast hydrolysate (YH) has multiple salutary biological activities. Nevertheless, the application of YH in broiler production is limited. This study was conducted to evaluate the protective effects of YH derived from Saccharomyces cerevisiae by exploring growth performance, serum parameters, organs relative weight, carcass traits, meat quality and antioxidant status of broilers. RESULTS Supplementing YH linearly and quadratically improved (P < 0.05) body weight gain and gain‐to‐feed ratio compared to that in the control group. Triglycerides, low‐density lipoprotein cholesterol and total cholesterol in serum, the decline in pH and cooking loss of breast muscle, and malonaldehyde concentration in serum and liver were decreased linearly and/or quadratically by YH (P < 0.05), whereas high‐density lipoprotein cholesterol in serum, superoxide dismutase (SOD) and glutathione peroxidase (GSH‐Px) activities in serum, GSH‐Px activity in liver, glutathione content in serum and liver, eviscerated yield rate and chest muscle yield, and the relative weight of spleen and liver were linearly and/or quadratically increased (P < 0.05). Moreover, YH enhanced the mRNA levels of nuclear factor erythroid 2‐related factor 2, heme oxygennase‐1 (HO‐1), GSH‐Px1 and SOD1 (linear and/or quadratic, P < 0.05). CONCLUSION Dietary YH beneficially affected growth performance, serum parameters, organ relative weight, carcass traits, meat quality and antioxidant status in broilers, indicating its potential application as a promising feed additive in broiler production. © 2021 Society of Chemical Industry.

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Over-processed meat and bone meal and phytase effects on broilers challenged with subclinical necrotic enteritis: Part 1. Performance, intestinal lesions and pH, bacterial counts and apparent ileal digestibility

et al. 2020

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This feeding study investigated the hypothesis that over-processing of meat and bone meal (MBM) would impair the performance, gut health and ileal digestibility of nutrients in birds challenged with necrotic enteritis (NE). The effect of phytase (500 vs. 5,000 FTU/kg) was also examined using manufacturers recommended matrix values for 500 FTU for both levels. Ross 308 male broilers ( n = 768) were assigned to 8 diets, with 6 replicate pens per diet and 16 birds per replicate pen using a randomized design with a factorial arrangement of treatments. Factors were NE challenge (no or yes), MBM (as received or over-processed), and phytase level (500 or 5,000 FTU/kg). Half of the birds were challenged with 5,000 oocysts of field strains of Eimeria acervulina and Eimeria brunetti , and 2,500 oocysts of Eimeria maxima on d 9 and 10 8 CFU/mL of Clostridium perfringens strain EHE-NE18 on d 14 and 15 post-hatch. Challenge × MBM interactions were detected for weight gain (WG), feed conversion ratio (FCR) and feed intake (FI) at d 14, 21 and 28, showing that challenged birds fed over-processed MBM had decreased WG ( P < 0.05) and FI ( P < 0.05) at d 14, increased FCR ( P < 0.05) at d 21 and decreased WG ( P < 0.05) and FI ( P > 0.05) at d 28. Birds fed low phytase had increased livability ( P < 0.05) at d 42. The challenge increased the prevalence and severity of NE induced lesions in the jejunum ( P < 0.05) and ileum ( P < 0.05). The birds fed over-processed MBM had decreased pH in the jejunum ( P < 0.05) and ileum ( P < 0.05) at d 16. High phytase increased apparent ileal digestibility (AID) of Ca ( P < 0.05) and P ( P < 0.05), and over-processed MBM increased AID of carbon (C; P < 0.05) and Ca ( P < 0.05) at d 29. The challenge increased the caecal counts of Lactobacillus spp. ( P < 0.05) and C. perfringens ( P < 0.05) at d 16. The results indicated that supplementation of diets with high phytase reduces the negative impact on performance from over-processed MBM during NE as a result of increased nutrient digestibility.

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Nucleotide-rich yeast extract fed to broiler chickens challenged with Eimeria: impact on growth performance, jejunal histomorphology, immune system, and apparent retention of dietary components and caloric efficiency

Cited by 19 publications

References 37 publications

Utility of Feed Enzymes and Yeast Derivatives in Ameliorating Deleterious Effects of Coccidiosis on Intestinal Health and Function in Broiler Chickens

Utility of Feed Enzymes and Yeast Derivatives in Ameliorating Deleterious Effects of Coccidiosis on Intestinal Health and Function in Broiler Chickens

Effects of yeast hydrolysate on growth performance, serum parameters, carcass traits, meat quality and antioxidant status of broiler chickens

Over-processed meat and bone meal and phytase effects on broilers challenged with subclinical necrotic enteritis: Part 1. Performance, intestinal lesions and pH, bacterial counts and apparent ileal digestibility

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