The electromagnetic induction quenching approach has been widely applied in the engine industry, especially in relation to parts made of metal materials, such as crankshafts. To this end, the reinforcing effect of this technique has been quantitatively studied. Using this approach, we first performed multi-physics simulations to obtain key information, such as the temperature and residual stress distributions. Then, the fatigue limit load was predicted according to the simulation results and the indirect-defined theory of critical distance (ITCD) model. Finally, the feasibility of this prediction method was verified by standard bending fatigue experiments. The results of the prediction method were accurate and consistent with the experimental results, with wide popularization and application prospects.