In biological systems, the MHD boundary layer bioconvection flow through permeable surface has several applications, including electronic gadgets, heating systems, building thermal insulation, geological systems, renewable energy, electromagnetism and nuclear waste. The bioconvection caused by the hydromagnetic flow of a special form of water-based nanoliquid including motile microorganisms and nanoparticles across a porous upright moving surface is investigated in this report. The combination of motile microbes and nanoparticles causes nanofluid bioconvection is studied under the cumulative impact of magnetic fields and buoyancy forces. The Brownian motion, thermophoresis effects, heat absorption/generation, chemical reaction and Darcy Forchhemier impact are also unified into the nonlinear model of differential equations. The modeled boundary value problem is numerically computed by employing a suitable similarity operation and the parametric continuation procedure. The parametric study of the flow physical parameters is evaluated versus the velocity, energy, volume fraction of nanoparticles, motile microorganisms’ density, skin friction, Sherwood number and Nusselt number. It has been observed that the velocity profile reduces with the effect of porosity parameter k1, inertial parameter k2, Hartmann number and buoyancy ratio. While the energy transition profile significantly enhances with the flourishing values of Eckert number Ec, heat absorption/generation Q and Hartmann number respectively.