Numerical simulation for treatment of hypothermia based on vascular interventional direct heating system

Hou, Yi; Qiao, Yuanyuan; Zhang, Dajin; Shi, Chenxi; Liu, Jing; He, Zhi‐Zhu; Rao, Wei

doi:10.1016/j.jtherbio.2018.06.009

Cited by 2 publications

(3 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Sun et al reported an intriguing transformation behavior of LMMPs under a space-restricted two-phase condition [65] . When the LMMPs were cooled in a solution with a higher melting point, the basal solution would first solidify and trap the LMMPs.…”

Section: Transformability Of Lmmps/lmnpsmentioning

confidence: 99%

“…When LMMPs underwent phase change, they would expand and form spiny deformations to cause mechanical damage to the surrounding ice within only 1 ms [85] , as shown in Figure 5C i. The deformation ratio of LMMPs is determined by the properties of the surrounding solution [Figure 5C ii] [65] . In this way, an enhanced cryoablation efficiency would be realized by simply employing LMMPs as cryosurgery agents.…”

Section: Lm Deformation Enhanced Destruction Of Tumorsmentioning

confidence: 99%

“…Reproduced with permission[85] Copyright 2020, Wiley-VCH GmbH; (ii) Deformation ratio of LMNPs in different solutions. Reproduced with permission[65] Copyright 2020, American Chemical Society; (iii) Post-cryoablation tumor volume under different conditions. Reproduced with permission[85] Copyright 2020, Wiley-VCH GmbH; (D) Liquid metal transformer enabled endosomal escape for enhanced cryo-treatment.…”

mentioning

confidence: 99%

See 2 more Smart Citations

Liquid metals enabled advanced cryobiology: development and perspectives

Yang,

Lu,

Rao

2024

Soft Sci

Self Cite

View full text Add to dashboard Cite

Cryosurgery and cryopreservation, as two important categories in cryobiology, have been impeded by the poor thermal conductivity of biological tissues or specimens. To improve this, diverse adjuvants, e.g., carbon-based materials, metallic nanoparticles, metallic oxide nanoparticles, etc ., have been exploited to improve the heat transfer in heat-targeted regions to increase the tumor elimination efficiency as well as the post-thaw viability of cryopreserved specimens. Nevertheless, these materials suffer poor thermal conductivities, controversial biosafety problems, and high expense. Gallium and its alloys, as a class of room-temperature liquid metals (LMs), have been widely studied in the past decade for their low melting point, minor toxicity, outstanding transformability, and conductivity. Integrated with these superior properties, they have been widely applied in multiple fields, such as thermal management, flexible electronics, and soft robotics. Recently, our laboratory has been devoted to fusing LMs with cryobiology and has made a series of progress. In this article, we will first briefly introduce preparation pathways to LM-based functional nanomaterials and composites. Then, how these materials realize improvement in biological heat transfer will be presented, followed by a discussion about the biosafety of these materials, which is an essential concern for the cryobiological field. Recent studies employing LMs in advanced cryosurgery and cryopreservation will also be highlighted. The present challenges and prospects of LMs towards further development in cryobiology will be put forward to point out the possible research direction.

show abstract

Section: Transformability Of Lmmps/lmnpsmentioning

confidence: 99%

Section: Lm Deformation Enhanced Destruction Of Tumorsmentioning

confidence: 99%

mentioning

confidence: 99%

See 1 more Smart Citation