Numerical simulation of hemodynamic parameters of turbulent and pulsatile blood flow in flexible artery with single and double stenoses

Jahangiri, Mehdi; Saghafian, Mohsen; Sadeghi, Mahmood

doi:10.1007/s12206-015-0752-3

Cited by 24 publications

(27 citation statements)

References 27 publications

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“…6 show that the maximum pressure and, consequently, the mean arterial pressure in the pre-stenotic segment increase with increasing stenosis percent. Our previous experimental and numerical studies in the absence of magnetic field showed that a stenosis of more than 70% and 70%-70% is critical [72,73] and increases the pressure non-physiologically. This is consistent with the results of other studies [80][81][82][83][84].…”

Section: Resultsmentioning

confidence: 96%

“…The number of computational elements was 125,660, the lowest mesh quality was 0.3617, and the maximum growth rate was 1.095. The dimensions of the artery, the artery wall properties, and the geometry of the stenosis are similar to those in [49,50,72,73]. When a physical model is selected in COMSOL to model the fluid flow, the solver and its related settings are usually determined automatically due to the conditions and geometry.…”

Section: Problem Statementmentioning

confidence: 99%

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The impact of uniform magnetic field on the pulsatile non-Newtonian blood flow in an elastic stenosed artery

Sadeghi

Jahangiri

Saghafian

2020

J Braz. Soc. Mech. Sci. Eng.

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Since the effect of magnetic fields on blood flow is not fully understood or studied comprehensively, this paper, for the first time, addresses the effect of uniform magnetic fields with different intensities on the pulsatile non-Newtonian blood flow in an elastic artery with axially symmetrical single and double stenoses using the commercial software COMSOL Multiphysics 5.1. The results are suggestive that an increase in the percent stenosis increases the pressure drop, which is more dramatic in double stenosis. Moreover, for a given percent stenosis, increasing the Hartmann (Ha) number, in addition to increasing the pressure drop, increases the amount by which the pressure drop is raised. The shear stress results revealed that increasing the magnetic field intensity results in the reduction of the vortex region formed in the back of the stenosis, reducing the area prone to disease, which can resolve pathological issues. The impact of the magnetic field was found to be decreased by increasing the percent stenosis. It was also observed that the percentage difference between the maximum wall shear stresses for various percent stenoses is reduced by increasing the Ha number for both single and double stenoses.

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Section: Resultsmentioning

confidence: 96%

Section: Problem Statementmentioning

confidence: 99%

The impact of uniform magnetic field on the pulsatile non-Newtonian blood flow in an elastic stenosed artery

Sadeghi

Jahangiri

Saghafian

2020

J Braz. Soc. Mech. Sci. Eng.

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“…Sensitivity studies were carried out with a time step of 0.001 and maximum iteration number of 50, and the results confirmed insignificant differences. In order to exclude the transient effects, the simulations were run for at least three cycles, as was done in previous works [41].…”

Section: Statement Of the Problemmentioning

confidence: 99%

“…(5) to (7) are available in Ref. [26].Generally, the solid elastodynamics momentum equation is used to express the mechanical behavior of the artery wall [28]:…”

Section: Introductionmentioning

confidence: 99%

Computational studies of comparative and cumulative effects of turbulence, fluid–structure interactions, and uniform magnetic fields on pulsatile non-Newtonian flow in a patient-specific carotid artery

Moradicheghamahi

Jahangiri

Mousaviraad

et al. 2020

J Braz. Soc. Mech. Sci. Eng.

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Clinical evidence has shown that hemodynamics plays an important role in vascular diseases that hemodynamic parameters are highly dependent on the elasticity of the artery wall. Since so far, no study has not been done about turbulent and non-Newtonian blood flow in carotid artery under a magnetic field, in this study we use computational fluid dynamics and fluid-structure interaction (FSI) models to study the hemodynamics of a patient-specific carotid artery. The comparative and cumulative effects of turbulence modeling, arterial wall elasticity, and magnetic field intensities are investigated by quantifying their effects on different variables of interest. These variables include blood pressure, time-averaged wall shear stress, relative residence time (RRT), and oscillating shear index (OSI), which are important in the onset and development of atherosclerosis. The results showed that the effects of turbulence are significant for predictions of OSI, while for other variables the turbulent simulation results were comparable to laminar simulations. The effects of wall elasticity were significant for all variables, such that FSI modeling will be essential for an accurate computational framework. The effects of magnetic fields were also found to be relatively significant. By increasing Hartman number from zero to five, the maximum shear stress was reduced by about 10%. Other effects of increased intensity of magnetic field included reduction in the average amount of RRT, sharp decrease in the OSI > 0 region, and transfer of maximum OSI from distal part of carotid sinus to the proximal part.

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“…Sadeghi et al (2011) investigated the intravascular stenosis severity and suggested that increase in stenosis severity affects wall shear stress, peripheral stress, and their amplitude and the angle between them. Jahangiri, et al (2015a) investigated single and dual stenosis with 30%, 50%, 70%, and 80% severities and suggested that endothelial cells were damaged in the case of 70% severity.…”

Section: Introductionmentioning

confidence: 99%

Study of Pulsatile Flow in Common Carotid Artery with Different Stenosis' Shapes within Various Wall Conditions

Bayat

Tavakoli

2019

JAFM

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Recently, due to the development of CFD techniques, many attempts have been made to simulate the initiation and progression of atherosclerosis. In recent works, various curves have been suggested to model the stenosis shape. However, little effort has been made to study the importance of the stenosis shape on the flow behavior. In this study, four types of stenosis with asteroid, Gaussian, semicircle , and sinusoidal shapes were simulated in order to study the effect of the stenosis shape on flow behavior and diagnosis parameters. Shear stress and flow behavior were investigated in the common carotid artery with stenosis severities of 30%, 40%, and 50%. Flow was assumed to be unsteady and the inlet to be a pulsatile flow. Two cases of Newtonian and non-Newtonian fluids were simulated. The no-slip and permeable boundary conditions were imposed on the outer walls. To examine the effect of the location of stenosis, modeling was conducted at various locations. The results showed that the maximum shear stress occurs in the Gaussian stenosis at the opening of the stenosis. Semicircle , sinus, and asteroid shapes had the next largest shear stress values. Additionally, the location of stenosis had a negligible effect on the maximum shear stress. However, flow resistance increased with increasing the stenosis's distance from the beginning of the artery. This study indicates that stenosis shape highly affects the flow characteristics, and stenosis severity is not the only parameter that is important. Hence, the stenosis shape should be considered when simulating atherosclerosis.

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Numerical simulation of hemodynamic parameters of turbulent and pulsatile blood flow in flexible artery with single and double stenoses

Cited by 24 publications

References 27 publications

The impact of uniform magnetic field on the pulsatile non-Newtonian blood flow in an elastic stenosed artery

The impact of uniform magnetic field on the pulsatile non-Newtonian blood flow in an elastic stenosed artery

Computational studies of comparative and cumulative effects of turbulence, fluid–structure interactions, and uniform magnetic fields on pulsatile non-Newtonian flow in a patient-specific carotid artery

Study of Pulsatile Flow in Common Carotid Artery with Different Stenosis' Shapes within Various Wall Conditions

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