The paper deals with the Stress Intensity Factor assessment of cracks at the intersection of holes loaded by internal pressure. Triangular flaws are considered at the intersection of two holes inside a specific specimen. The research examines the influence of hole diameter ratio D 1 /D 2 and the angle between their axes α. Numerical analysis is performed to determine the Stress Intensity Factors (SIF) of mode I in many different geometric configurations. The actual shape of a real crack nucleated at the intersection of two cylindrical holes is subject to variable internal pressure and is usually geometrically complex. The Stress Intensity Factor changes along the crack contour and the crack shape development is controlled by its local value, e.g. during a fatigue loading. In general, the estimation of the Stress Intensity Factors of cracks with a complex shape is made by means of numerical methods since closed form solutions in literature are limited. However, in order to solve the problem of crack propagation more quickly, in the case of a crack corner at the intersection between two cylindrical holes, we can assume, in agreement with scientific literature, a symmetrical triangular crack shape and the Stress Intensity Factor are only calculated at the middle of the crack. Obviously, this is a strong approximation, but this allows a reduction in the computation effort for crack growth rate assessments and safety evaluation. In this paper, the weight function technique is used by integrating the actual stress field evaluated in the uncracked model. The method of the weight function is of general validity and the weight function is related to the displacement components close to the crack front, as proposed by Bueckner and Rice. From a computational point of view, the use of the three-dimensional weight function is complex and in scientific literature a weight function of general validity is not available. Nevertheless, thanks to the work conducted by Petroski and Achenbach, Shen and Glinka, an efficient generalised weight function has been adopted and then developed by Sha and Yang [9], which considers a series expansion of non-singular terms. In this way, the integration of the weight function, multiplied by a nominal stress, is made along a line and not in a two-dimensional domain. In this preliminary work, according to Herz et al., we consider a weight function with three terms by assuming a priori the coefficients of the second and third non-singular terms. This contribution is essentially an extension of a previous paper by Herz et al. They only considered the case of D 1 /D 2 =1 and =90° (D i are the diameters of the two cylindrical holes and a is the angle between their axis). Here, we extend the analysis to D 1 /D 2 equal to 2, 4 and 8 with an of 60 and 45 degrees.