Numerical study of dc-biased ac-electrokinetic flow over symmetrical electrodes

Ng, Wee Yang; Ramos, António; Lam, Yee Cheong; Rodríguez, Isabel

doi:10.1063/1.3668262

Cited by 6 publications

(4 citation statements)

References 34 publications

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“…Theoretical modeling of the frequency-dependent pumping was further developed [49] and used to simulate different aspects of the ACEO pumping [50,51]. Furthermore, the effect of several parameters and pumping configurations were investigated, such as studying the effect of channel height, electrochemical reactions, and non-linear surface capacitance of the Debye layer [52]; controlling the pumping direction by switching the voltage using an inclined electrode array [53,54], pumping of two different electrolytes simultaneously through microchannels [55], bubble-free pumping [56,57] as well as ACEO pumping using biased AC/DC signals [48,[58][59][60][61], pulse voltage waveforms [57], square pole-slit electrode arrays [62], and arrays of asymmetric ring electrode pairs in the cylindrical microchannels [63]. Also, the comparison between fluid velocity on arrays of identical electrodes with AC voltage and a traveling-wave potential demonstrated that traveling-wave potential resulted in a higher fluid velocity [64,65].…”

Section: Aceo Micropumpsmentioning

confidence: 99%

“…The ICEK micropumps introduced so far are categorized as ACEO micropumps where the fluid velocity in the range of 0.1-2.5 mm s −1 has been reported with applying DC electric signals [58,60]. Huang et al [69] used ACEO micropumps functioning under AC voltage to generate fluid velocity in microchannels as high as 1.3 mm s −1 .…”

Section: Iceo Micropumps Bazant and Squiresmentioning

confidence: 99%

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Induced-charge electrokinetics in microfluidics: a review on recent advancements

Manshadi

Mohammadi

Zarei

et al. 2020

J. Micromech. Microeng.

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Applying an external electric field over a polarizable electrode or object within microchannels can induce an electric double layer (EDL) around channel walls and create induced-charge electrokinetics (ICEK) within channels. The primary consequence of the induced charge is the generation of micro-vortices around the polarizable electrode or object, presenting great potential for various microfluidic applications. This review presents the advances in theoretical, numerical and experimental studies on the physics and applications of ICEK within microfluidics. In particular, the characteristics and performance of ICEK-based microfluidic components in active micromixers, micropumps, and microvalves are critically reviewed, followed by discussing the applications of ICEK in electrophoresis and particle/cell manipulation within microfluidics. Furthermore, the opportunities and challenges of ICEK-based microfluidic devices are highlighted. This work facilitates recognizing deliverable ICEK-based microfluidic technologies with unprecedented functionality for the next generation of biomedical applications with predictable manufacturability and functionality.

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Section: Aceo Micropumpsmentioning

confidence: 99%

Section: Iceo Micropumps Bazant and Squiresmentioning

confidence: 99%

Induced-charge electrokinetics in microfluidics: a review on recent advancements

Manshadi

Mohammadi

Zarei

et al. 2020

J. Micromech. Microeng.

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show abstract

“…W.Y. Ng et al investigated the mechanism of the flow and concluded that a conductivity gradient drives fluid flow [38,39]. Deionized (DI) water [37,40], a 10 −4 M solution of KCl (conductivity 1 mS m −1 ), and a CuSO 4 solution (conductivity 4 mS m −1 ) [38] were used as working fluids.…”

Section: Introductionmentioning

confidence: 99%

Scalable Parallel Manipulation of Single Cells Using Micronozzle Array Integrated with Bidirectional Electrokinetic Pumps

et al. 2020

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High throughput reconstruction of in vivo cellular environments allows for efficient investigation of cellular functions. If one-side-open multi-channel microdevices are integrated with micropumps, the devices will achieve higher throughput in the manipulation of single cells while maintaining flexibility and open accessibility. This paper reports on the integration of a polydimethylsiloxane (PDMS) micronozzle array and bidirectional electrokinetic pumps driven by DC-biased AC voltages. Pt/Ti and indium tin oxide (ITO) electrodes were used to study the effect of DC bias and peak-to-peak voltage and electrodes in a low conductivity isotonic solution. The flow was bidirectionally controlled by changing the DC bias. A pump integrated with a micronozzle array was used to transport single HeLa cells into nozzle holes. The application of DC-biased AC voltage (100 kHz, 10 Vpp, and VDC: −4 V) provided a sufficient electroosmotic flow outside the nozzle array. This integration method of nozzle and pumps is anticipated to be a standard integration method. The operating conditions of DC-biased AC electrokinetic pumps in a biological buffer was clarified and found useful for cell manipulation.

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“…The resulting temperature distribution surrounding the electrode changes the local conductivity and permittivity, causing electrothermal (ET) fluid flow. [10][11][12][13][14][15][16][17][18][19][20] ET fluid flow has been used previously for mixing particle suspensions. 15 Taking the advantage of manipulating the fluid by ET forces and the particles by DEP forces, the present study applies these techniques for developing micromixers and microconcentrators.…”

Section: Introductionmentioning

confidence: 99%

Study on the use of dielectrophoresis and electrothermal forces to produce on-chip micromixers and microconcentrators

2012

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The present study uses the dielectrophoresis (DEP) and electrothermal (ET) forces to develop on-chip micromixers and microconcentrators. A microchannel with rectangular array of microelectrodes, patterned either on its bottom surface only or on both the top and the bottom surfaces, is considered for the analysis. A mathematical model to compute electrical field, temperature field, the fluid velocity, and the concentration distributions is developed. Both analytical and numerical solutions of standing wave DEP (SWDEP), traveling wave DEP (TWDEP), standing wave ET (SWET), and traveling wave ET (TWET) forces along the length and the height of the channel are compared. The effects of electrode size and their placement in the microsystem on micromixing and microconcentrating performance are studied and compared to velocity and concentration profiles. SWDEP forces can be used to collect the particles at different locations in the microchannel. Under positive and negative DEP effect, the particles are collected at electrode edges and away from the electrodes, respectively, irrespective of the position, size, and number of electrodes. The location of the concentration region can be shifted by changing the electrode position. SWET and TWET forces are used for mixing and producing concentration regions by circulating the fluid at a given location. The effect of forces can be changed with the applied voltage. The TWDEP method is the better method for mixing along the length of the channels among the four options explored in the present work. If two layers of particle suspension are placed side by side in the channel, triangular electrode configuration can be used to mix the suspensions. Triangular and rectangular electrode configurations can efficiently mix two layers of particle suspension placed side-by-side and one-atop-the-other, respectively. Hence, SWDEP forces can be successfully used to create microconcentrators, whereas TWDEP, SWET, and TWET can be used to produce efficient micromixers in a microfluidic chip.

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Numerical study of dc-biased ac-electrokinetic flow over symmetrical electrodes

Cited by 6 publications

References 34 publications

Induced-charge electrokinetics in microfluidics: a review on recent advancements

Induced-charge electrokinetics in microfluidics: a review on recent advancements

Scalable Parallel Manipulation of Single Cells Using Micronozzle Array Integrated with Bidirectional Electrokinetic Pumps

Study on the use of dielectrophoresis and electrothermal forces to produce on-chip micromixers and microconcentrators

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