Hydrodynamic interaction continues to be a major contributory factor in marine casualties and hazardous incidents, in particular in the case of overtaking operations. The situation becomes even worse when the overtaking operation occurs in shallow and narrow channels where the interaction can cause the vessels to collide and, in one case has caused the capsizal of the smaller vessel with loss of life. The aim of this paper is to propose a methodology, as well as to discuss the development of a numerical program, to predict the ship-to-ship interaction during overtaking operations in shallow water.Since the vessels involved in the present study have different forward speeds, an uncoupled method will be used to solve the boundary value problem. The in-house multi-body hydrodynamic interaction program MHydro, which is based on the 3D Rankine source method, will be used and extended here to investigate the interactive forces and wave patterns between two ships during an overtaking operation.The present calculations are compared with model test results as well as published CFD calculations.Very satisfactory agreement has been obtained, which indicates that the proposed methodology and developed program are successfully validated to predict the hydrodynamic interaction between two ships advancing in confined waters. The discussions also highlight the speed effects.