Nursery Exposure of 528 Newborns to a Nurse With Pulmonary Tuberculosis

Burk, John R.; Bahar, David; Wolf, Frederick; Greene, J. E.; Bailey, W. E.

doi:10.1097/00007611-197801000-00004

Cited by 35 publications

(17 citation statements)

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“…The isolation rooms at this hospital used UVGI and enhanced ventilation. Burk et al (1978) reported the lack of active TB or positive skin tests among 514 infants who were exposed over a 3 month period to a nursery supervisor with pulmonary TB. The nursery also used UVGI and enhanced ventilation.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of a Methodology for Quantifying the Effect of Room Air Ultraviolet Germicidal Irradiation on Airborne Bacteria

Miller¹,

Macher²

2000

Aerosol Science and Technology

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ABSTRACT. As a result of the recent resurgence in tuberculosis (TB) and the increasing incidence of multidrug-resistant TB, there has been renewed interest in engineering controls to reduce the spread of TB and other airborne infectious diseases in high-risk settings. Techniques such as the use of lamps that produce ultraviolet germicidal radiation may reduce exposure to infectious agents by inactivating or killing microorganisms while they are airborne. We designed and evaluated a test method to quantitatively estimate the ef cacy of germicidal lamps, in conjunction with dilution ventilation, for reducing the concentration of viable airborne bacteria. Bacterial particles were generated in a 36 m 3 room and collected with midget impingers at 5 -7 locations. The effectiveness of the control technique was determined by comparing concentrations of culturable airborne bacteria with and without the control in operation. Results for a single, 15 W germicidal lamp showed reductions of 50% for Bacillus subtilis (B. subtilis) and Micrococcus luteus (M. luteus); tests with Escherichia coli (E. coli) showed nearly 100% reduction (E. coli were isolated only from the sampler nearest the aerosol source when the lamp was operating). The addition of louvers to a lamp greatly reduced its ef cacy. Decay experiments showed that roughly 4 -6 equivalent air changes per hour were achieved for B. subtilis with one or two lamps operating. These preliminary experiments demonstrated that this methodology was well suited for these evaluations and identi ed factors that could be modi ed to re ne the study design for future work.

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Section: Introductionmentioning

confidence: 99%

Evaluation of a Methodology for Quantifying the Effect of Room Air Ultraviolet Germicidal Irradiation on Airborne Bacteria

Miller¹,

Macher²

2000

Aerosol Science and Technology

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“…[2][3][4][5][6][7][13][14][15][16][17] This may add confidence that a staged approach for future TB screening activities in neonatal settings can be a safe and cost-effective alternative to initially screening all potentially exposed neonates.…”

Section: Resultsmentioning

confidence: 99%

“…2,5,[13][14][15][16] We estimate the total cost to the hospital of this screening investigation was $128 430. This may underestimate the true cost as some items could not be quantified, including the cost of screening the 15 neonates and their relatives who attended other facilities for screening, the cost to families of travel to the clinics and pharmacy, and the investigation hotline.…”

Section: Resources Usedmentioning

confidence: 99%

Costs of a contact screening activity in a neonatal intensive care unit

Fisher¹,

Cook²,

Marks³

2013

NSW Public Health Bull.

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“…Very few nosocomial outbreaks involving newborns have been described to date [6][7][8][9][10][11][12][13][14]. Here we report a case of TB that occurred in a four-month old infant potentially linked to a nurse diagnosed with TB who worked in the maternity ward when the child was born.…”

Section: Epidemiological Backgroundmentioning

confidence: 99%

Suspected transmission of tuberculosis in a maternity ward from a smear-positive nurse: preliminary results of clinical evaluations and testing of neonates potentially exposed, Rome, Italy, 1 January to 28 July 2011

et al. 2011

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We report preventive measures adopted after tuberculosis (TB) transmission from a nurse to a newborn assessed in late July 2011. All exposed neonates born between January and July 2011 were clinically evaluated and tested by QuantiFERON TB gold in-tube; newborns testing positive were referred for prophylaxis. Of 1,340 newborns, 118 (9%) tested positive and no other active cases of TB were found. Active surveillance for TB will be continued over the next three years for all those exposed.

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Nursery Exposure of 528 Newborns to a Nurse With Pulmonary Tuberculosis

Cited by 35 publications

References 0 publications

Evaluation of a Methodology for Quantifying the Effect of Room Air Ultraviolet Germicidal Irradiation on Airborne Bacteria

Evaluation of a Methodology for Quantifying the Effect of Room Air Ultraviolet Germicidal Irradiation on Airborne Bacteria

Costs of a contact screening activity in a neonatal intensive care unit

Suspected transmission of tuberculosis in a maternity ward from a smear-positive nurse: preliminary results of clinical evaluations and testing of neonates potentially exposed, Rome, Italy, 1 January to 28 July 2011

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