Nurses' Experiences of Palliative Care in the Neonatal Intensive Care Unit: A Qualitative Study

Abstract

Introduction:Palliative care for newborns and their families is urgent. Nurses' experiences need to be considered in order to implement palliative care. Therefore, the present study was conducted to explain the Nurses' Experiences of Palliative Care in the NICU.Methods: This study was conducted by qualitative content analysis in the neonatal intensive care units of Isfahan, Iran, in 2020. Inclusion criteria for nurses were the consent to participate in the study and experience of caring for the newborn and their family at the end of life. For data collection by the purposeful sampling method, in-depth semi-structured interviews were conducted with 12 nurses. Interviews were recorded, typed, and analyzed. Goba and Lincoln criteria were used to ensure the rigor of the data. Results:The first theme was palliative care for the newborn. This theme consists of two categories: "compassionate end-of-life care" and " spiritual end-of-life care". The second theme was palliative care of the family. This theme consists of two categories: "Palliative care of the family before the death of the newborn" and "Palliative care of the family after the death of the newborn ". Conclusion:The results of this research are in line with the WHO definition of palliative care in pediatric, which refers to the active total care of the child's body, mind and spirit, and family support. The results of this research are used to improve the care of infants and families at the end of life and death for officials and nurses of NICU.

Labdane-Type Diterpenes from the Aerial Parts of Rydingia persica: Their Absolute Configurations and Protective Effects on LPS-Induced Inflammation in Keratinocytes

“…Furthermore, extracts and subfractions obtained from liquid–liquid extraction, along with selected isolated compounds, were examined for their activity on HaCaT cells in inflammatory conditions, by investigating their activity on IL-6 and TNF-α release and nitrotyrosine formation, along with their effect on claudin-1 and occludin expression. It may be concluded that the aerial parts of R. persica are a rich source of labdane-type diterpenoids with anti-inflammatory and potential wound-healing activity in keratinocytes, thus supporting the traditional application of this plant for the treatment of inflammation and wounds. , …”

“…It may be concluded that the aerial parts of R. persica are a rich source of labdane-type diterpenoids with anti-inflammatory and potential woundhealing activity in keratinocytes, thus supporting the traditional application of this plant for the treatment of inflammation and wounds. 14,15 ■ EXPERIMENTAL SECTION General Experimental Procedures. Optical rotations were measured using a JASCO P-2000 polarimeter (Easton, MD, USA).…”

“…Furthermore, F16-S7 (39 mg) was subjected to silica gel column chromatography (Ø = 1 cm, l = 25 cm) and eluted with CH 2 Cl 2 −acetone (90:10, v/v) to afford F16-S7-P23-26 (5, 4.2 mg). Additionally, F16-S13 (14 mg) was purified using a silica gel column (Ø = 0.5 cm, l = 20 cm), eluted with CH 2 Cl 2 −acetone (80:20, v/v), to afford F16-S13-P27-40 (14,3 13 C NMR (CDCl 3 ), see Tables 1 and 2 1 H and 13 C NMR and DP4+ and ECD Calculations. Compounds were drawn in Maestro (Schrodinger Ltd., release 2018) and subjected to conformational analysis in MacroModel 09, using OPLS-3 as force field in the gas phase.…”

“…14 The aerial parts of R. persica were traditionally used by local tribes of the region and in Iranian traditional medicine as an insect repellent and for the treatment of diabetes, rheumatism, cardiac diseases, gastric discomfort, and wounds. 14,15 A previous in vivo study of a methanolic extract of R. persica revealed that the extract could significantly improve the wound-healing process. 15 However, the study was not supported by either an appropriate phytochemical characterization or the identification of the active principles of R. persica responsible for facilitating the wound-healing process.…”

Opening a Donor Management Center

“…It has been well documented that caring for brain-dead organ donors can be ethically and morally distressing to bedside staff, both in the OR and the ICU. This is related to complex emotional and moral responses to the concept of brain death, the challenges of working with and supporting grieving families, and the need to balance maintaining the dignity of the donor with the requirements of optimizing organs for recovery 7, 9-12…”