Nursing Personnel in the Era of Personalized Healthcare in Clinical Practice

Spanakis, Marios; Patelarou, Athina; Patelarou, Evridiki

doi:10.3390/jpm10030056

Cited by 18 publications

(14 citation statements)

References 96 publications

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“…Nowadays, the utilization of state-of-the-art technologies in clinical practice, along with the further understanding of biology and pharmacology, can assist medical personnel to improve their healthcare [53][54][55]. Aiming to reduce the risk of ADE/ADRs, the early detection of problems and good communication between healthcare providers and patients, regular review of treatment, continuing education, adoption of preventive measures, development of quality of care, organization in the work environment and the development of a critical view of uniform patient safety assessment standards are important parameters in modern therapeutic practice [22,56].…”

Section: Discussionmentioning

confidence: 99%

Impact of Adverse Drug Reactions in Patients with End Stage Renal Disease in Greece

Spanakis

Roubedaki

Tzanakis

et al. 2020

IJERPH

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Background: Patients with end-stage renal disease (ESRD) require specialized therapeutic interventions. The decreased renal function that modulates the physiology and presence of comorbidities is often associated with variations in the pharmacological response, thus increasing the risk of adverse drug events or reactions (ADE/ADRs) from co-administered drugs. Methods: A cross-sectional study to record comorbidities, drug–drug interactions (DDIs), ADE/ADRs in patients with chronic kidney disease of stage five in Greece. The study enrolled 60 patients of mean age 64.8 ± 12.9 years, undergoing hemodialysis three times a week. Demographic and social factors, comorbidities, laboratory test data, medication regimens, DDIs and the reporting of ADE/ADRs were analyzed. Results: Cardiovascular diseases and diabetes were the main comorbidities. In total, 50 different DDIs of various clinical significance were identified. CNS, GI-track, and musculoskeletal-system-related ADE/ADRs were most often reported by patients. ADE/ADRs as clinical outcome from DDIs were associated in 64% of the total identified DDIs. There was a positive trend between number of medications, ADE/ADRs report and DDIs. Conclusions: The impact of ADE/ADRs in ESRD patients should be always considered. Guidelines as well as continuous training in the context of evidence-based clinical practice by healthcare personnel on therapy administration and prevention of adverse events are important.

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Section: Discussionmentioning

confidence: 99%

Impact of Adverse Drug Reactions in Patients with End Stage Renal Disease in Greece

Spanakis

Roubedaki

Tzanakis

et al. 2020

IJERPH

Self Cite

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“…Thus, all the gathered knowledge can be filtered through appropriate channels from pharmacovigilance regulatory bodies to be evaluated, revised, and return to enrich the clinical protocols ( Figure 3 ). Such an active “pharmacovigilant” role of healthcare professionals will boost also public confidence in their healthcare eco-systems against misinformation and same time will advance their role in the new era of healthcare [ 150 , 151 , 152 , 153 ].…”

Section: Healthcare Personnel In Covid-19 Clinics: Identifying and Manage Ddis And Adrsmentioning

confidence: 99%

Drug Interactions for Patients with Respiratory Diseases Receiving COVID-19 Emerged Treatments

Spanakis

Patelarou

et al. 2021

IJERPH

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Pandemic of coronavirus disease (COVID-19) is still pressing the healthcare systems worldwide. Thus far, the lack of available COVID-19-targeted treatments has led scientists to look through drug repositioning practices and exploitation of available scientific evidence for potential efficient drugs that may block biological pathways of SARS-CoV-2. Till today, several molecules have emerged as promising pharmacological agents, and more than a few medication protocols are applied during hospitalization. On the other hand, given the criticality of the disease, it is important for healthcare providers, especially those in COVID-19 clinics (i.e., nursing personnel and treating physicians), to recognize potential drug interactions that may lead to adverse drug reactions that may negatively impact the therapeutic outcome. In this review, focusing on patients with respiratory diseases (i.e., asthma or chronic obstructive pulmonary disease) that are treated also for COVID-19, we discuss possible drug interactions, their underlying pharmacological mechanisms, and possible clinical signs that healthcare providers in COVID-19 clinics may need to acknowledge as adverse drug reactions due to drug-drug interactions.

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“…10 Nurses have known to play an important role in educating and providing personalized care to patients whether it is management of viral hepatitis or COVID-19 cases. 11 However, additional burden of increasing patients, predisposes them to psychological distress. 12,13 Despite all these issues, nursing professionals have emerged as frontline warriors in fight against novel coronavirus.…”

Section: Introductionmentioning

confidence: 99%

Hepatitis update program: need of the situation to co-manage viral hepatitis and COVID-19

et al. 2021

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Background: Government of India has taken several initiatives towards combating viral hepatitis but due to sudden surge in COVID-19 cases resulted in suspension of viral hepatitis program related activities. Moreover, COVID-19 has several liver related complications hence more special precautions are required to manage patients with known liver diseases. Nurses play an important role in management of any disease. However, there is limited knowledge among nurses on co-management of COVID-19 and viral hepatitis. With this background, two-day training program for nursing professionals was conceptualized under the project PRAKASH to educate and train the nurses about co-management of COVID-19 and viral hepatitis. Methods: A pre-post study was undertaken among nurses who have registered for hepatitis update program. The online link to 25-knowledge related questions along with demographic variables was shared with the registered participants. Paired t test and other statistical analyses were done using SPSS v-21. Level of significance was taken at p<0.05Results: A total of 1151 responses were received out of 1477 trained participants. The mean age of the nursing participants was 32.5±6.95 years. The overall mean knowledge score in the pre-assessment was found to be 15.47±4.13 out of 25, which further increased to 20.72±3.81 in the post-assessment. Gender, type of facility, education, willingness to get trained and prior training related to viral hepatitis were found to be independently associated with pre-knowledge score.Conclusions: Training programs should be encouraged for diseases which are of public health importance and can’t be ignored with respect to increasing burden of COVID-19 cases.

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Nursing Personnel in the Era of Personalized Healthcare in Clinical Practice

Cited by 18 publications

References 96 publications

Impact of Adverse Drug Reactions in Patients with End Stage Renal Disease in Greece

Impact of Adverse Drug Reactions in Patients with End Stage Renal Disease in Greece

Drug Interactions for Patients with Respiratory Diseases Receiving COVID-19 Emerged Treatments

Hepatitis update program: need of the situation to co-manage viral hepatitis and COVID-19

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