Background: The Evaluation of Health Technologies is a multidisciplinary activity that systematically, transparent, impartial, effectively summarizing the safety, clinical efficacy and effectiveness, cost, cost-effectiveness, organizational mplications, social consequences, legal, ethical and organizational considerations of the application of a health technology The Evaluation of Health Technologies has significantly improved the decision-making process. To evaluate the reliability of technological measuring devices used in patient care. Methods: This study is a descriptive and observational study. The research was conducted between December 2019-April 2020 in Mardin Province hospitals. The population of the study consisted of 245 patients who were hospitalized in the clinics of these hospitals, over the age of 18 and 65 years agreed to participate in the study. The data were collected through a questionnaire. Descriptive statistics (number, percentage and average) were used to evaluate the data. In order to conduct the study, written permission was obtained from the relevant institutions, ethics committee permission from the university and written consent from the individuals participating in the study. Results: The average age of the patients participating in the study was 42 years, and 35.1% were male, 64.9% were female, 82.0% were married and 69.4% were literate or primary school graduates. It was determined that 45% of the patients had at least one chronic disease and 38% of them used medication continuously. While the mean hunger blood glucose levels of the patients participating in the study were 128 mg / dl in measurements with the glucometer device, blood glucose laboratory levels obtained from the vein were found to be 122 mg / dl. Pulses of the patients were found to be 85 / min on average with a pulse oximeter device, and 87 / min on average in measurement by palpation from the artery method. While the temperature measurement average values of the patients were found to be 36.6 ° C with the forehead non-contact measurement device, the average temperature was found to be 35.7 ° C with the armpit digital measurement device. Conclusion: The use of technology in nursing care applications is an indispensable element. However, for the safe use of technological devices in nursing care, it is extremely important to measure the measurement devices used correctly. Significant differences were detected in the blood glucose levels measured with the glucometer device. We can say that there is a difference in thermometers, but pulse oximetry devices measure safely. More comprehensive research is recommended on this subject.