Background The idea of “life force” or “subtle pranic energy,” sometimes referred to as prana, ki, qi, vital force, and scientifically accepted as biofield, is prevalent across many cultures. Objectives This review's objective is to synthesize data from studies that looked at a range of physical, psychological, and biofield sensations while experiencing prana and receiving biofield therapies. Method We looked for qualitative, exploratory, and mixed-method studies on subtle pranic energy perceptions, as well as the physical and emotional experiences connected to biofield therapeutic procedures, through searches in 3 electronic databases, including PubMed, Web of Science, and Scopus. Based on inclusion and exclusion criteria, ninteen studies were appropriate for this review. The results were synthesized using the 6 steps of the thematic analysis approach. Results The first concept, “energy experiences,” comprises 4 themes that describe participants’ sensations of prana (awareness of temperature variation; presence of energy; physical sensation of energy; and magnetic sensation). The second concept, “positive experiences,” consists of 3 themes that describe the benefits of undergoing biofield therapy on the physical and emotional conditions of the participants (positive affective experiences; positive physical sensations; and positive valued experiences). The third concept, “experience of awareness,” describes how participants become aware of their mental activities (awareness of mental activities). Conclusion Our knowledge of perceptions and experiences related to biofield therapy is enhanced by this meta-synthesis. It gave a comprehensive picture of the enormous sensations and advantages that were felt when engaging in biofield practices.