Nutraceutical or Pharmacological Potential of Moringa oleifera Lam.

Kou, Xianjuan; Li, Biao; Olayanju, Julia B.; Drake, Justin M.; Chen, Ning

doi:10.3390/nu10030343

Cited by 277 publications

(212 citation statements)

References 74 publications

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“…Cultivation by cuttings and transplantation are also used, but the plants do not develop taproots, making them more sensitive to drought and wind. Still, propagation by cuttings seems to be preferred by some farmers, since it promises a quick flowering and fruiting rates, and gives the best quality fruits [4,22]. Still, transplanting young plants requires utmost care as the tap roots are tender [33,43].…”

Section: Cultivation and Climatic Requirementsmentioning

confidence: 99%

“…Several factors contribute for this widespread interest, including its easy cultivation in a variable range of climatic and geographical conditions, its high production yields, the multipurpose uses of all its vegetative structures (leaves, flowers, immature pods, seeds, etc. ), with nutritional relevance for humans and animals, a traditional use for medicinal purposes, in agroforestry systems and for water purification [2][3][4][5][6]. Its seeds are rich in oil, used for cosmetic and perfume production since ancient times, as lubricants in machinery and, more recently, for biodiesel production [7][8][9].…”

Section: Introductionmentioning

confidence: 99%

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The Potential of Some Moringa Species for Seed Oil Production

2018

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There is an increasingly demand for alternative vegetable oils sources. Over the last decade there has been fast growing interest in Moringa oleifera Lam., particularly due to its high seed oil yield (30-40%), while other Moringa species with similar potentialities are reducing their representativeness worldwide. This review reinforces the interesting composition of Moringa oil, rich in oleic acid and highly resistant to oxidation, for industrial purposes, and shows that other Moringa species could also be exploited for similar purposes. In particular, Moringa peregrina (Forssk.) Fiori has an interesting oil yield and higher resistance to pest and diseases, and Moringa stenopetala (Bak. f.) Cuf. is highlighted for its increased resistance to adverse climate conditions, of potential interest in a climate change scenario. Exploring adapted varieties or producing interspecies hybrids can create added value to these less explored species, while renewing attention to endangered species. Moringa seed oil can be extracted by conventional methods or using physical methods (pressing), creating diverse products from a compositional perspective, able to serve both the biodiesel and food industries.

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Section: Cultivation and Climatic Requirementsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

The Potential of Some Moringa Species for Seed Oil Production

2018

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“…It is present in tropical and subtropical areas of Asia and Africa. MO is known for its nutritional and pharmacological importance [20][21][22]. All over the world, MO has been extensively and traditionally used to alleviate several afflictions, such as hepatorenal, cardiovascular, hematological, and gastrointestinal disorders.…”

Section: Introductionmentioning

confidence: 99%

“…All over the world, MO has been extensively and traditionally used to alleviate several afflictions, such as hepatorenal, cardiovascular, hematological, and gastrointestinal disorders. In addition, it has efficient anti-inflammatory, antimicrobial, and anti-oxidative properties [22][23][24]. Natural herbalists use the different parts of MO, such as leaves, roots, flowers, fruit, and seeds, to obtain different extracts of Moringa.…”

Section: Introductionmentioning

confidence: 99%

Moringa Oleifera Leaf Extract Repairs the Oxidative Misbalance following Sub-Chronic Exposure to Sodium Fluoride in Nile Tilapia Oreochromis niloticus

Ahmed

Sadek

Soliman

et al. 2020

Animals

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The potential antioxidant property of Moringa oleifera (MO) has been the recent focus of an increased number of studies. However few studies investigated its antioxidative ability against sodium fluoride-induced redox balance breakdown in Oreochromis niloticus. Thus, this study evaluates the effects of MO against the oxidative stress induced by sub-chronic exposure to sodium fluoride (NaF). A total of 264 fish (40 ± 3 g BW) were used to calculate the 96 hr-LC50 of NaF and perform the sub-chronic exposure study. 96 hr-LC50 of NaF was calculated as (61 mg/L). The 1/10 dose of the calculated 96 hr-LC50 (6.1 mg/L) was used to complete the sub chronic exposure for eight weeks. Fish were divided into four groups (n = 51; three replicates each); control, non-treated group; NaF group (exposed to NaF 6.1 mg/L); MO group (treated with 1% MO of diet); and NaF+MO (exposed to NaF 6.1 mg/L and treated with 1% MO of diet). The results revealed that the sub-chronic exposure to NaF (6.1 mg/L) was substantially increased malondialdehyde (MDA) and decrease the activities of superoxide dismutase (SOD), catalase (CAT), glutathione reduced (GSH), glutathione peroxidase (GPx), and total antioxidant capacity (TAC) in the gills, liver, kidney, and muscle tissue in a time-dependent manner. In addition, a significant reduction in mRNA expression of GST in the liver was reported following NaF exposure. On the contrary, dietary supplementation of MO to NaF-exposed fish resulted in a significant reduction in MDA levels, and a significant elevation of SOD, CAT, GSH, GPx, and TAC activities in a time-dependent manner, in addition to significant elevation of GST mRNA expression in liver tissue. It could be concluded that a 1% MO (w/w) ration is a promising antioxidant plant that may successfully use to interfere with the oxidation processes induced by NaF in various tissues of Oreochromis niloticus.

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“…Moringa oleifera leaf extract (MLE) possesses anticancer, antiinflammatory, bacteriocidal, hypocholesterolemic, antioxidant, neuro-and hepatoprotective properties [46][47][48]. Ameliorative effects of Moringa oleifera have been studied against many chemicals by several researchers in fishes and mammals [21,49,50].…”

Section: Discussionmentioning

confidence: 99%

Imidacloprid Toxicity and Its Attenuation by Aqueous Extract of Moringa Oleifera Leaf in Zebra Fish, Danio Rerio

Yadav

Ahmad

Zahra

2020

Int J Curr Pharm Sci

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Objective: Imidacloprid (IMC) is a systemic chloro-nicotinyl insecticide that is applied in crop fields to control a wide variety of harmful insects and pests. The objective of the present study was to evaluate the mitigating effects of Moringa leaf extract (MLE) against Imidacloprid (IMC) induced mortality after acute toxicity bioassay in zebrafish, Danio rerio. Methods: The fishes were exposed to various concentrations of IMC to estimate the LC50 values at different exposure periods using the probit analysis. To assess the attenuating effect on mortality fishes were exposed to different concentrations of MLE along with 24 and 96 h LC50 of IMC. Mortality rate of fishes was recorded during all experimental periods. Results: The LC50 values were found to be 0.423, 0.352, 0.297 and 0.270 ml/l after 24, 48, 72 and 96 h respectively. The upper confidence limits were 0.491, 0.408, 0.334 and 0.302 ml/l and lower confidence limits were 0.355, 0.296, 0.260 and 0.238 ml/l for 24, 48, 72 and 96 h respectively. The fishes remain alive at 12 ml/l and 10 ml/l of MLE against 24 and 96 h LC50 respectively. Some behavioral responses such as violent, sluggish and erratic movement, respiratory distress, mucous secretion all over the body, discoloration were also observed in IMC treated fishes in comparison to MLE treated fishes. Conclusion: These findings demonstrated that MLE has mitigating effects against the toxic influence of IMC on mortality in zebra fishes which is attributed to its antioxidant effects.

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Nutraceutical or Pharmacological Potential of Moringa oleifera Lam.

Cited by 277 publications

References 74 publications

The Potential of Some Moringa Species for Seed Oil Production

The Potential of Some Moringa Species for Seed Oil Production

Moringa Oleifera Leaf Extract Repairs the Oxidative Misbalance following Sub-Chronic Exposure to Sodium Fluoride in Nile Tilapia Oreochromis niloticus

Imidacloprid Toxicity and Its Attenuation by Aqueous Extract of Moringa Oleifera Leaf in Zebra Fish, Danio Rerio

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