Nutraceuticals in the management of obesity

Nijhawan, Priya; Behl, Tapan

doi:10.1016/j.obmed.2019.100168

Cited by 22 publications

(12 citation statements)

References 32 publications

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“…Natural or processed food that, beyond providing energy and basic nutrients (fatty acids, proteins, dietary fibre, carbohydrates, vitamins, minerals, antioxidants, prebiotics, probiotics, symbiotics, and phytochemicals), has an additional beneficial impact on health, physical performance, or state of mind is called functional food [ 1 , 2 , 4 , 5 , 8 , 9 ]. The consumption of this type of food strengthens the immune system, averts diseases (prevents from heart, brain, and kidney-related diseases), decreases cholesterol levels, reduces lactose intolerance, remission of Crohn’s disease, relieves diarrhoea, inhibits cancer cell proliferation, helps to recover from physical and mental disorders, and can also delay the ageing process [ 10 , 11 ].…”

Section: Introductionmentioning

confidence: 99%

“…On the other hand, nutraceuticals are concentrated bioactive compounds refined from food and are the foremost products used in healthcare [ 7 , 9 , 12 , 13 , 14 ]. They can be found in various pharmaceutical forms—liquids, pills, capsules, tablets, powders, potions, solutions, and vials [ 2 , 7 , 9 ]. They are defined as any food (or a part thereof) with benefits for human health additional to the basic nutritional value found in foodstuffs [ 14 , 15 ].…”

Section: Introductionmentioning

confidence: 99%

“…On the other hand, nutraceuticals are concentrated bioactive compounds refined from food and are the foremost products used in healthcare [7,9,[12][13][14]. They can be found in various pharmaceutical forms-liquids, pills, capsules, tablets, powders, potions, solutions, and vials [2,7,9].…”

Section: Introductionmentioning

confidence: 99%

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Effect of Botanical Extracts on the Growth and Nutritional Quality of Field-Grown White Head Cabbage (Brassica oleracea var. capitata)

et al. 2021

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Nutraceuticals and functional foods are gaining more attention amongst consumers interested in nutritious food. The consumption of foodstuffs with a high content of phytochemicals has been proven to provide various health benefits. The application of biostimulants is a potential strategy to fortify cultivated plants with beneficial bioactive compounds. Nevertheless, it has not yet been established whether the proposed higher plants (St. John’s wort, giant goldenrod, common dandelion, red clover, nettle, and valerian) are appropriate for the production of potential bio-products enhancing the nutritional value of white cabbage. Therefore, this research examines the impact of botanical extracts on the growth and nutritional quality of cabbage grown under field conditions. Two extraction methods were used for the production of water-based bio-products, namely: ultrasound-assisted extraction and mechanical homogenisation. Bio-products were applied as foliar sprays to evaluate their impact on total yield, dry weight, photosynthetic pigments, polyphenols, antioxidant activity, vitamin C, nitrates, micro- and macroelements, volatile compounds, fatty acids, sterols, and sugars. Botanical extracts showed different effects on the examined parameters. The best results in terms of physiological and biochemical properties of cabbage were obtained for extracts from common dandelion, valerian, nettle, and giant goldenrod. When enriched with nutrients, vegetables can constitute a valuable component of functional food.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Effect of Botanical Extracts on the Growth and Nutritional Quality of Field-Grown White Head Cabbage (Brassica oleracea var. capitata)

et al. 2021

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“…In another way, it can be well-defined as the combination of nutrition and pharmaceutics in a single platform. It has gained much attention because of the potential clinical beneficial effects on reducing the risks of cancer, cholesterol, cardiovascular diseases, diabetes, and obesity, etc …”

Section: Introductionmentioning

confidence: 99%

Microfluidic Assembly: An Innovative Tool for the Encapsulation, Protection, and Controlled Release of Nutraceuticals

Liu

Singh

Zhang

et al. 2021

J. Agric. Food Chem.

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Nutraceuticals have been gradually accepted as food ingredients that can offer health benefits and provide protection against several diseases. It is widely accepted due to potential nutritional benefits, safety, and therapeutic effects. Most nutraceuticals are vulnerable to the changes in the external environment, which leads to poor physical and chemical stability and absorption. Several researchers have designed various encapsulation technologies to promote the use of nutraceuticals. Microfluidic technology is an emerging approach which can be used for nutraceutical delivery with precise control. The delivery systems using microfluidic technology have obtained much interest in recent years. In this review article, we have summarized the recently introduced nutraceutical delivery platforms including emulsions, liposomes, microspheres, microgels, and polymer nanoparticles based on microfluidic techniques. Emphasis has been made to discuss the advantages, preparations, characterizations, and applications of nutraceutical delivery systems. Finally, the challenges, several up-scaling methods, and future expectations are discussed.

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“…Several studies explore the action of anti-inflammatory agents [ 13 , 14 , 15 , 16 ], such as proteins of vegetable origin [ 14 , 15 ] and bioactive peptides [ 17 ].…”

Section: Introductionmentioning

confidence: 99%

Hydrolyzed Proteins and Vegetable Peptides: Anti-Inflammatory Mechanisms in Obesity and Potential Therapeutic Targets

et al. 2022

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Chronic low-grade inflammation is present in overweight and obesity, causing changes in several metabolic pathways. It impairs systemic functioning and positively feeds back the accumulation of more adipose tissue. Studies with hydrolyzed proteins and plant peptides have demonstrated a potential anti-inflammatory and immunomodulatory effect of these peptides. However, it is challenging and necessary to explore the mechanism of action of such molecules because understanding their effects depends on their structural characterizations. Furthermore, the structure might also give insights into safety, efficacy and efficiency, with a view of a possible health application. Thus, the present narrative review aimed to discuss the mechanisms of action of hydrolyzed proteins and plant peptides as anti-inflammatory agents in obesity. Keywords and related terms were inserted into databases for the search. Based on the studies evaluated, these biomolecules act by different pathways, favoring the reduction of inflammatory cytokines and adipokines and the polarization of macrophages to the M2 phenotype. Finally, as a future perspective, bioinformatics is suggested as a tool to help understand and better use these molecules considering their applicability in pre-clinical and clinical studies.

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Nutraceuticals in the management of obesity

Cited by 22 publications

References 32 publications

Effect of Botanical Extracts on the Growth and Nutritional Quality of Field-Grown White Head Cabbage (Brassica oleracea var. capitata)

Effect of Botanical Extracts on the Growth and Nutritional Quality of Field-Grown White Head Cabbage (Brassica oleracea var. capitata)

Microfluidic Assembly: An Innovative Tool for the Encapsulation, Protection, and Controlled Release of Nutraceuticals

Hydrolyzed Proteins and Vegetable Peptides: Anti-Inflammatory Mechanisms in Obesity and Potential Therapeutic Targets

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