Nutrient intake and progression of coronary artery disease

Watts, Gerald F.; Jackson, Penny; Mandalia, Sundhiya; Brunt, J. N. H.; Lewis, Eve S.; Coltart, D J; Lewis, Barry

doi:10.1016/0002-9149(94)90003-5

Cited by 82 publications

(37 citation statements)

References 24 publications

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“…In the present study cholesterol intake was 220 mg/d, which represents a low mean intake compared to previous studies where it has varied from 160 mg/d in women with CABG (Allen & Blumenthal, 1995) to 350 mg/d in men with angina or AMI (BoltonSmith et al, 1992;Watts et al, 1994). The ®ber intake has varied from 14 g/d in women with CABG (Allen & Blumenthal, 1995) to 28 g/d in men with AMI or angina pectoris receiving dietary therapy (Watts et al, 1994).…”

Section: Discussioncontrasting

confidence: 64%

“…(Fehily et al, 1989) only 21% of the men with AMI in a group which had not been given advice about fat intake achieved the recommended fat intake. In other studies the mean intake of fat has been far from recommended, even about 40 E% (Fehily et al, 1987;Bolton-Smith et al, 1992;Watts et al, 1994).…”

Section: Discussionmentioning

confidence: 94%

“…A basis for this mistrust could be that the adherence to the dietary goals has been poor in the studies included in their review. Generally, the mean intakes of fat and saturated fat have been above the recommended levels in CHD patients analyzed in a prospective cohort (Allen & Blumenthal, 1995), in population based surveys (Fehily et al, 1987;Bolton-Smith et al, 1992) or in the baseline phase of trials (Karvetti, 1981;Fehily et al, 1989;Shenberger et al, 1992;Watts et al, 1994). Earlier studies have included mainly patients with myocardial infarction or angina except for the studies performed on patients with coronary artery bypass grafting (Allen & Blumenthal, 1995;Shenberger et al, 1992).…”

Section: Introductionmentioning

confidence: 99%

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Concordance of diet with the recommended cholesterol lowering diet in patients with coronary heart disease

et al. 1998

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Section: Discussioncontrasting

confidence: 64%

Section: Discussionmentioning

confidence: 94%

Section: Introductionmentioning

confidence: 99%

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Concordance of diet with the recommended cholesterol lowering diet in patients with coronary heart disease

et al. 1998

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“…Destaca-se que os tratamentos de suplementação com óleo de babaçu, aumentaram tanto os níveis de triglicerídeos quanto os de colesterol com o decorrer do experimento. O aumento da concentração de colesterol no sangue das éguas pode ser explicado por vários estudos Keys 42 , Ohtani et al 43 , Watts et al 44 , reportaram que a elevação da colesterolemia ocorre em virtude do aumento no consumo de gordura saturada, nesse caso proveniente da suplementação com óleo de babaçu. Assim Knuiman et al 45 , com humanos, e Watson, Packard e Shepherd 41 com éguas, verificaram que a concentração de colesterol plasmático é significativamente relacionada com triglicerídeos.…”

Section: Resultsunclassified

Efeito da suplementação da dieta com óleo de babaçu sobre a composição do sangue e leite de éguas em lactação

Spers

Fernandes

et al. 2006

Braz. J. Vet. Res. Anim. Sci.

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ResumoFoi investigada a suplementação de dietas com óleo de babaçu nos níveis de (0, 4, 8 e 16%) na composição do sangue e leite de éguas em lactação. Utilizaram-se 16 éguas em lactação, sem raça definida com peso vivo médio de 441,2 kg. As éguas foram suplementadas com 1,5% do peso vivo com uma mistura composta de quirera de milho, farelo de trigo e farelo de soja com 16% de proteína bruta. A água e o volumoso constituído de Napier e suplemento mineral, foram oferecidos ad libitum. Colocadas em baias individuais com 4 x 5m as éguas recebiam as dietas tratamento uma vez ao dia.Elas foram alimentadas durante 42 dias. Coletaram-se amostras de 50 ml de sangue para análise de triglicerídeos e colesterol total e 250 ml de leite colhido manualmente para as análises de acidez, teor de gordura e colesterol. O sangue apresentou, ao término do experimento, os seguintes teores: triglicerídeos (24, 32, 28 e 25 mg dl ) e para o leite, os teores encontrados foram: (acidez 10, 9, 8 e 7 ºD), gordura (0,6; 1,1; 0,9 e 0,9 %), colesterol na gordura do leite (366,5; 308,6; 447,9 IntroduçãoOs eqüinos, à semelhança dos outros animais, exigem na sua alimentação vários nutrientes como, energia, carboidratos e lipídeos, proteínas e ainda minerais e vitaminas. Esses nutrientes atendem às necessidades das diferentes fases da vida animal: manutenção, crescimento, engorda, gestação, lactação e trabalho. De todas as fases citadas, a lactação é a mais exigente, pois apresenta a maior demanda de nutrientes, principalmente de energéticos. A égua, nas primeiras semanas de lactação, além dos nutrientes para a manutenção, pode requerer vários outros considerando a possibilidade de estar em nova gestação, de ser submetida a trabalho, ainda que moderado, e de produzir grandes quantidades de leite, cujo principal substrato energético é a lactose. Mas, para atender a toda essa exigência, deve ser nutricionalmente muito bem manejada. Isso, porém, não ocorre, pois em geral associa-se a produção de leite apenas com a produção comercial da vaca leiteira, não se levando em conta que todos os mamíferos apresentam tal capacidade. Apesar de a vaca ser especialista em produzir grande quantidade de leite por um período mais longo que outras fêmeas, a égua pode produzir até 24 kg de leite por dia. Uma das falhas mais comuns cometidas na criação de eqüinos, tanto pelos proprietários como pelos próprios nutricionistas, é a de sub-alimentar as fêmeas durante a lactação. Torna-se indispensável,

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“…Consequently, from this study it is not possible to identify the crucial components responsible for the development of atherosclerosis, which may be any constituent of the food groups or any nutrient normally accompanying the consumption of these food stuffs (Robins & Greenland, 1992;Watts et al, 1994). Also, food-frequency is a method to detect differences between cases and controls, but not to estimate absolute amounts of energy, for example.…”

Section: Discussionmentioning

confidence: 99%

Nutrition is a powerful independent risk factor for coronary heart disease in women—The CORA Study: a population-based case–control study

2005

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Background: It is still common practice to rely mostly on drug treatment for preventing cardiovascular disease, although a healthy nutrition has been defined that may prevent most premature cardiovascular events. Objectives: This research raises the question of the magnitude of the effect of nutrition on cardiovascular disease independent of that of clinical risk factors, which are the targets of drug therapy. Design: The study of coronary risk factors for atherosclerosis in women compares clinical, biochemical, and lifestyle factors in 200 consecutive pre-and postmenopausal women with incident coronary heart disease (CHD) to those in 255 age-matched population-based controls. Results: Cases reported a higher intake of energy, predominantly through animal fat and protein reflected by a higher consumption of meat and sausage, while controls ate more fruit and vegetables. Multivariate analysis adjusted for clinical risk factors depicted a high intake of meat and sausage and a low consumption of fruit and vegetables as independent risk factors with an odds ratio of 2.5 (95% confidence interval 1.1-5.7) and 0.7 (95% confidence interval 0.5-1.0) for each 100 g per day, respectively. These dietary factors were found to be significantly more pronounced in cases with any clinical risk factor identified in this population as compared to controls with the same risk factors. Conclusions: The CORA-study clearly indicates a major impact of dietary habits on CHD in women independent of, and additive to, that of conventional risk factors. Thus, in clinical practice, the potential of nutrition as part of a healthy lifestyle is commonly greatly underestimated in favour of drug treatment. Sponsorship: German Stifterverband für die Wissenschaft.

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Nutrient intake and progression of coronary artery disease

Cited by 82 publications

References 24 publications

Concordance of diet with the recommended cholesterol lowering diet in patients with coronary heart disease

Concordance of diet with the recommended cholesterol lowering diet in patients with coronary heart disease

Efeito da suplementação da dieta com óleo de babaçu sobre a composição do sangue e leite de éguas em lactação

Nutrition is a powerful independent risk factor for coronary heart disease in women—The CORA Study: a population-based case–control study

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