Nutrition of toxic epidermal necrolysis

Esposito, G.; Gravante, Gianpiero; Piazzolla, Michele; Marianetti, M.; Delogu, Daniela; Montone, Antonio

doi:10.1111/j.1365-277x.2006.00685.x

Cited by 5 publications

(2 citation statements)

References 4 publications

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“…[ 3 ] Others state that third space loss phenomenon and changes in vascular permeability are absent, contrary to burn patients, with less need for fluid-aggressive therapy. [ 24 25 ]…”

Section: Ase R Eportmentioning

confidence: 99%

“…High nutritional requirements due to an hypermetabolic response, appear to be related to TBSA affected. [ 3 25 ] Nutrient absorption can be altered by gastrointestinal mucosa involvement. Some authors suggest avoiding nasogastric tube because of gastrointestinal mucosae potential involvement;[ 26 27 ] however, this might be the only feeding alternative.…”

Section: Ase R Eportmentioning

confidence: 99%

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Lyell's syndrome and antimalarials: A case report and clinical review

Nunes

Santareno

Guerreiro

et al. 2017

J Global Infect Dis

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Toxic epidermal necrolysis (TEN) or Lyell's syndrome is a rare, however, life-threatening mucocutaneous disorder with an epidermal detachment of a total body surface area (TBSA) of >30%. It is triggered by an idiosyncratic immune-allergic reaction to a drug, with many possible drugs implicated. Treatment success relies on early diagnosis and withdrawal of suspected/causative drug(s) and supportive care. Clinical evidence for specific therapies is still sparse. It is described a case of Lyell syndrome by sulfonamides for chemoprophylaxis of malaria. The patient presented with an extensive, rapidly evolving skin detachment, which progressed, despite supportive therapy, involving about 80% of TBSA. This led us to initiate a course of immunoglobulin with good clinical response. The aim of this work is to provide a discussion of the case and simultaneously make a practical literature review of TEN.

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“…[ 3 ] Others state that third space loss phenomenon and changes in vascular permeability are absent, contrary to burn patients, with less need for fluid-aggressive therapy. [ 24 25 ]…”

Section: Ase R Eportmentioning

confidence: 99%

Section: Ase R Eportmentioning

confidence: 99%

Lyell's syndrome and antimalarials: A case report and clinical review

Nunes

Santareno

Guerreiro

et al. 2017

J Global Infect Dis

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Toxic epidermal necrolysis (Lyell's disease)

Lissia¹,

Mulas²,

Bulla³

et al. 2010

Burns

125

135

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Society of Dermatology Hospitalists supportive care guidelines for the management of Stevens-Johnson syndrome/toxic epidermal necrolysis in adults

Seminario‐Vidal

Kroshinsky

Malachowski

et al. 2020

Journal of the American Academy of Dermatology

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Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening conditions with high morbidity and mortality. Supportive care management of SJS/TEN is highly variable. A systematic review of the literature was performed by dermatologists, ophthalmologists, intensivists and gynecologists with expertise in SJS/TEN to generate statements for supportive care guideline development. Members of the Society of Dermatology Hospitalists (SDH) with expertise in SJS/TEN were invited to participate in a modified, online Delphi-consensus. 9-point Likert scale questionnaires regarding 135 statements were administered. The RAND/UCLA appropriateness method was employed to evaluate and select proposed statements for guideline inclusion; statements with median ratings of 6.5-9 and disagreement index ≤1 were included in the guideline. For the final round, the guidelines were appraised by all the participants. An evidence-based discussion and recommendations for hospital setting and care team, wound care, ocular care, oral care, urogenital care, pain management, infection surveillance, fluid and electrolyte management, nutrition and stress ulcer prophylaxis, airway management, and anticoagulation in adult patients with SJS/TEN are included.

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Nutrition of toxic epidermal necrolysis

Cited by 5 publications

References 4 publications

Lyell's syndrome and antimalarials: A case report and clinical review

Lyell's syndrome and antimalarials: A case report and clinical review

Toxic epidermal necrolysis (Lyell's disease)

Society of Dermatology Hospitalists supportive care guidelines for the management of Stevens-Johnson syndrome/toxic epidermal necrolysis in adults

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