Nutritional Clinical Studies in Dermatology

Abstract

Nutrition has long been associated with playing a principal and multifaceted • role in skin health, beauty, integrity, and aging, both directly or indirectly, through multiple pathways and cofactors implicated in skin biology. The onset and the clinical courses of various common skin diseases, including • acne, psoriasis, atopic dermatitis, and hair loss, have been shown to be critically affected by nutritional patterns and habits. Abnormal nutritional conditions, such as obesity anorexia nervosa, manifest in • specific cutaneous appearance features and altered function of the skin. Skin photoprotection, rendered by various nutrients, has been well documented. • Appropriate nutritional supplementation has been shown to exert beneficial • effects on impaired skin's structural and functional integrity, restore its appearance, and promote skin health.

Acne is an inflammatory disease and alterations of sebum composition initiate acne lesions

“…Evidence suggests that diet may influence acne, [61][62][63] whereas it is also an important source of substrate for the synthesis of sebaceous lipids. 61 This notion is supported also by the observation that sebum contains essential fatty acids, such as linoleate and oleate.…”

Skin Aging Remedies in Traditional Persian Medicine

“…Modern medicine believes that the main cause of skin aging contributes to environmental factors such as sunlight, air pollution, chemical and mechanical stimulation (1-3). On the other hand, internal factors such as malnutrition, obesity, alcohol consumption, smoking and etc can also speed up the process of aging with production of oxygen free radicals and DNA damage (2,4,5). Also in skin aging, loss of lipid and water content in different skin layers is one of the important damaging factors.…”

“…Although sunscreens and topical antioxidants can postpone the process of skin aging, the role of dietary supplements and nutrients in preventing skin aging has been one of the most noteworthy factors (5). Long-term dietary supplements consumption in the form of chemical agents are likely to cause potential adverse effects and oral administration of natural foods such as fruits, vegetables, beans and grains can decrease the mentioned risk (6)(7)(8)(9).…”

La nutrición como condicionante de la salud de la piel

“…Existe poca información suficientemente contrastada sobre los efectos en la piel de los aportes de los diferentes nutrientes 2,3 . El agua representa aproximadamente el 70 % de su composición, a la que en su variación pueden acompañarla diversas sales con valor nutricional.…”

“…Otra vitamina liposoluble, la vitamina E, es un antioxidante que modula los daños producidos por radicales libres originados tras la exposición a la irradiación UV e inhibe significativamente la degradación del colágeno. Junto con sus propiedades antioxidantes, podría regular negativamente la inflamación de la piel atenuando la producción de prostaglandinas, citocinas proinflamatorias, ciclooxigeneasa-2 y NADPH oxidasa 1,3 .…”