Nutritional Considerations of Critically Ill Hematopoietic Cell Transplantation Patients

Fuji, Shigeo; Cheng, Jessica

doi:10.1007/978-3-031-28797-8_34

Cited by 1 publication

(2 citation statements)

References 34 publications

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“…For HSCT patients who are unable to maintain their oral route of nutrition due to gastrointestinal system failure, the nutritional support is indicated as either enteral nutrition (EN) or parenteral nutrition (PN) [ 38 , 56 , 57 , 58 ]. According to ASPEN based on the theory, the benefit of EN is to maintain close connections between intraepithelial cells, creating blood flow and insisting that tropic endogenous agents (e.g., gastrin) are principal in the underlying stability of the GI system [ 23 ].…”

Section: Enteral Versus Parenteral Nutritionmentioning

confidence: 99%

“…These data demonstrate that short-term administration of Omega-3 has no benefit, but its long-term administration shows immunomodulatory and anti-inflammatory properties [ 89 ]. The inclusion of omega-3 PUFAs as a component of PN appears to be particularly beneficial in patients with intestinal GvHD, patients with hypertriglycerinaemia (to maintain a normal lipid ratio in PN) [ 58 ].…”

Section: Polyunsaturated Fatty Acidsmentioning

confidence: 99%

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The Critical Exploration into Current Evidence behind the Role of the Nutritional Support in Adult Patients Who Undergo Haematogenic Stem Cell Transplantation

et al. 2023

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Haematopoietic stem cell transplantation (HSCT) is a treatment option for many haematological conditions in patients of all ages. Nutritional support is important at each stage of treatment, but particular nutritional needs and dictated support occur during the preparatory (conditioning regimen) and post-transplant periods. Patients may require nutritional treatment by the enteral or parenteral route. The quantitative and qualitative composition of meals may change. Vitamin requirements, including vitamin D and vitamin C, might also be different. An adequately composed diet, adapted to the needs of the patient, may influence the occurrence of complications such as graft-versus-host disease (GvHD), gastrointestinal disorders, infections, and reduced survival time. Haematological diseases as well as transplantation can negatively affect the intestinal flora, with negative consequences in the form of mucosal inflammation and disorders of a functional nature. Currently, aspects related to nutrition are crucial in the care of patients after HSCT, and numerous studies, including randomized trials on these aspects, are being conducted. This study serves the critical analysis of current scientific evidence regarding nutritional support for patients after HSCT.

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