Nutritional Factors Adversely Influencing the Glucose/Insulin System

Fields, Meira

doi:10.1080/07315724.1998.10718768

Cited by 15 publications

(13 citation statements)

References 53 publications

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“…It was found that copper deficiency was associated with hepatic iron retention [8]. Iron is a strong oxidant which has the ability to generate reactive oxygen species.…”

Section: Discussionmentioning

confidence: 99%

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Dietary Intake and Serum and Hair Concentrations of Minerals and their Relationship with Serum Lipids and Glucose Levels in Hypertensive and Obese Patients with Insulin Resistance

Suliburska

Bogdański

Pupek-Musialik

et al. 2010

Biol Trace Elem Res

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Inadequate minerals intake, as well as disruption of some metabolic processes in which microelements are cofactors, are suggested to lead to the development of hypertension. The role of minerals in the pathogenesis of hypertension still remains to be explained. In the present study, we sought to determine associations between serum and hair mineral concentrations and serum lipids and glucose levels. Forty obese hypertensive subjects with insulin resistance and 40 healthy volunteers were recruited in the study. Blood pressure, BMI, and insulin resistance were recorded in all subjects. Levels of lipids, glucose, sodium and potassium, iron, copper, zinc, magnesium, and calcium were assessed in serum. Iron, copper, zinc, magnesium, and calcium were assessed in hair. Dietary intake of the analyzed minerals was estimated. We found distinctly higher concentrations of serum iron and serum and hair calcium as well as markedly lower levels of hair zinc in the hypertensive subjects. The study group manifested also significantly lower daily intake of calcium, magnesium, and iron. We observed a relationship between the concentrations of iron, zinc, and copper in serum and hair and high and low range of cholesterol, triglycerides, and glucose serum levels in the studied patients. Moreover, this study demonstrated significant correlation between serum and hair concentrations of selected minerals and their dietary intake and levels of serum lipids and glucose and blood pressure in the study and the control groups. The obtained results seem to indicate the association between lipid and glucose metabolism and iron, copper, zinc, and calcium concentrations in blood and hair of hypertensive and obese patients with insulin resistance.

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“…It was found that copper deficiency was associated with hepatic iron retention [8]. Iron is a strong oxidant which has the ability to generate reactive oxygen species.…”

Section: Discussionmentioning

confidence: 99%

“…Epidemiological and experimental studies showed that iron overload was associated with abnormalities of glucose homeostasis [8], whereas copper deficiency was associated with hepatic iron retention [8]. Magnesium has been postulated to play a role in glucose homeostasis and insulin action.…”

Section: Introductionmentioning

confidence: 99%

Dietary Intake and Serum and Hair Concentrations of Minerals and their Relationship with Serum Lipids and Glucose Levels in Hypertensive and Obese Patients with Insulin Resistance

Suliburska

Bogdański

Pupek-Musialik

et al. 2010

Biol Trace Elem Res

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“…In both muscle and adipose tissue, a high-fat diet resulted in decreased insulin receptor numbers, but no change in receptor affinity. The same diet has been shown to decrease insulinstimulated glucose transport and intracellular glucose metabolism (45). The type of fat and degree of saturation were also shown to play an important role for glucose metabolism.…”

Section: Methodsmentioning

confidence: 99%

Dietary Fat Is Associated With Metabolic Syndrome in Japanese Brazilians

Freire

Cardoso²,

Gimeno³

et al. 2005

Diabetes Care

139

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FOR THE JAPANESE-BRAZILIAN DIABETESSTUDY GROUP* OBJECTIVE -The aim of this study was to examine the association of nutrient intakes with metabolic syndrome in a Japanese descendant population at high risk for metabolic abnormalities. RESEARCH DESIGN AND METHODS-In a population-based study of Japanese Brazilians aged Ն30 years, 412 men and 465 women were studied. The diagnosis of metabolic syndrome was based on the National Cholesterol Education Program criteria modified for Asians. Food intake was assessed by a validated food frequency questionnaire.RESULTS -Men and women showed similar mean ages (55.7 Ϯ 12.7 and 54.4 Ϯ 11.9 years) and 49% (95% CI 44.8 -54.6) and 43% (38.4 -47.6) had metabolic syndrome, respectively. As expected, clinical parameters were less favorable in the subset of subjects with metabolic syndrome. Men with metabolic syndrome showed higher cholesterol (233.2 Ϯ 116.3 vs. 211.7 Ϯ 5.8 g/day, P Ͻ 0.05) and lower carbohydrate (288.5 Ϯ 45.8 vs. 300.1 Ϯ 39.8 g/day, P Ͻ 0.001) intakes than those without metabolic syndrome, but no difference was observed among the women. After adjusting for sex, age, smoking, education level, generation, physical activity, total energy, and dietary fiber intake, a positive association between metabolic syndrome and total fat intake was detected. Comparing people in the highest quintile of total fat consumption with those in the lowest quintile, odds ratio (OR) of metabolic syndrome was 5.0 ([95% CI 1.58 -16.00]; P Ͻ 0.005). In contrast, linoleic acid intake was inversely associated with metabolic syndrome (OR 0.50 [95% CI 0.26 -0.98]; P Ͻ 0.05). Considering food groups, after adjustments only fried food intake was shown to be associated with increased risk of metabolic syndrome.CONCLUSIONS -Despite the limitation of such a study design in investigating causeeffect relationships, our findings favor the hypothesis that dietary total fat may increase whereas linoleic acid intake may reduce the risk of metabolic syndrome in Japanese descendants living in Brazil. Diabetes Care 28:1779 -1785, 2005T he concept of metabolic syndrome includes a number of metabolic disturbances linked by insulin resistance, which increase cardiovascular risk (1). Weight gain (in particular, the abdominal depot of body fat) has a key role for the development of the syndrome.Lack of physical activity and certain dietary patterns, including high saturated fatty acid and low vegetable intake, contribute to weight gain and increase the risk of metabolic disturbances (2,3), whereas such potentially modifiable lifestyle factors may reduce cardiovascular risk.Metabolic syndrome is highly prevalent in the U.S. with an estimated 24% of the adult population affected (4). The National Cholesterol Education Program (5) defined metabolic syndrome based on several parameters including anthropometric measurements. However, anthropometric cutoffs to identify high-risk subjects may be influenced by ethnicity (6,7). Based on the fact that in Asian populations morbidity and mortality are occurring in people with ...

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“…Some aboriginal communities of the Interior of the Pacific North-West are known to collect Balsamroot (Balsamorhiza sagittata) and slowly pit-cook it for many hours, which converts most of the inulin into its fructose components resulting in a sweet tasting foodstuff (Peacock 1998). Humans however have a limited ability to metabolize fructose and if over-consumed it can potentially have detrimental effects on human health (Fields 1998;Elliott et al 2002;Basciano et al 2005). As a consequence, no Compositae crop has been domesticated as a source of starchy carbohydrates, unlike other large angiosperm families, such as Poaceae or Solanaceae.…”

Section: Nutritional Considerationsmentioning

confidence: 96%

Crop domestication in the Compositae: a family-wide trait assessment

Dempewolf

Rieseberg

Cronk

2008

Genet Resour Crop Evol

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Despite current recognition as the largest family of flowering plants (23,000 species ± 1000; Anderberg et al. 2007), the Compositae is home to comparatively few important crop species. To assess domestication levels in the Compositae, we developed an index that categorizes taxa according to the strength of domestication. Most Compositae species that are used by humans exhibit little or no evidence of domestication and only a handful have been strongly domesticated. Although the Compositae (along with Orchidaceae) has few domesticated taxa compared to other large families such as Fabaceae or Poaceae, Compositae species have features that should make them suitable for domestication and human consumption. These include high species diversity, global geographic distribution, good seed storability, and good seed oil quality. We propose that the paucity of domesticated species in this family can be attributed to a variety of factors, chiefly the prevalence of secondary defence compounds, the lack of carbohydrates that can be digested by the human gut and the predominantly mechanical or winddependent seed dispersal syndrome. We also discuss the relevance of genetic and cultural factors. Although few Compositae crops currently play a major role in global agriculture, many species hold unexploited potential, especially as novel crops for food and industrial applications.

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Nutritional Factors Adversely Influencing the Glucose/Insulin System

Cited by 15 publications

References 53 publications

Dietary Intake and Serum and Hair Concentrations of Minerals and their Relationship with Serum Lipids and Glucose Levels in Hypertensive and Obese Patients with Insulin Resistance

Dietary Intake and Serum and Hair Concentrations of Minerals and their Relationship with Serum Lipids and Glucose Levels in Hypertensive and Obese Patients with Insulin Resistance

Dietary Fat Is Associated With Metabolic Syndrome in Japanese Brazilians

Crop domestication in the Compositae: a family-wide trait assessment

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