Nutritional Management of End-Stage Renal Disease Patients Treated with Peritoneal Dialysis

Jiwakanon, Sirin; Mehrotra, Rajnish

doi:10.1016/b978-0-12-391934-2.00033-3

Cited by 1 publication

(1 citation statement)

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“…When optimal films containing 40 wt.% PDMS and 60 wt.% EC were employed, an adsorption of albumin of 0.07 ± 0.79 ng alb ng film −1 was observed when the sensors were exposed to an aqueous solution containing 40 mg mL −1 albumin. This concentration of albumin was chosen since it is in the range of the concentration typically found in normal patients [ 62 ]. On the contrary, a maximum adsorption was reported when pure EC was employed as the protective film, with 0.90 ± 0.05 ng alb ng film −1 .…”

Section: Resultsmentioning

confidence: 99%

Integration of an Aerosol-Assisted Deposition Technique for the Deposition of Functional Biomaterials Applied to the Fabrication of Miniaturised Ion Sensors

Ruiz-Gonzalez

Choy

2021

Nanomaterials

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Ion-selective electrodes are at the forefront of research nowadays, with applications in healthcare, agriculture and water quality analysis among others. Despite multiple attempts of miniaturization of these polyvinyl chloride (PVC) gel-based ion sensors, no ion-sensing devices with a thickness below the micrometer range, and operating using open circuit potential, have been developed so far. This work reports the causes of this thickness limitation in potassium-selective sensors. Highly homogeneous ion-sensing films were fabricated by a method based on aerosol assisted chemical vapour deposition, leading to smooth surfaces with 27 ± 11 nm of roughness. Such homogeneity allowed the systematic study of the performance and ionic diffusion properties of the sensing films at sub-micrometer scales. Sensitivities below the Nernst response were found at low thicknesses. The nature of this reduction in sensitivity was studied, and a difference in the superficial and bulk compositions of the films was measured. An optimal configuration was found at 15 µm, with a good selectivity against Na+ (KK+, Na+ = −1.8) a limit of detection in the range of 10−4 M and esponse time below 40 s. The stability of sensors was improved by the deposition of protective layers, which expanded the lifespan of the ion sensors up to 5 weeks while preserving the Nernst sensitivity.

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Section: Resultsmentioning

confidence: 99%