Nutritional Regulation of Gastric Secretion, Digestion and Emptying

Low, A. G.

doi:10.1079/nrr19900014

Cited by 86 publications

(48 citation statements)

References 132 publications

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“…4A). No other macronutrients were included because we aimed to assess the postprandial response of different amounts of whey protein without possible confounding effects of carbohydrate and/or fat intake on protein digestion and absorption kinetics (10,17). Consequently, nonisocaloric protein drinks were compared, and, as a result, different insulin responses were observed between experiments (Fig.…”

Section: Discussionmentioning

confidence: 99%

Amino acid absorption and subsequent muscle protein accretion following graded intakes of whey protein in elderly men

Pennings

Groen

Lange³

et al. 2012

American Journal of Physiology-Endocrinology and Metabolism

284

228

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Whey protein ingestion has been shown to effectively stimulate postprandial muscle protein accretion in older adults. However, the impact of the amount of whey protein ingested on protein digestion and absorption kinetics, whole body protein balance, and postprandial muscle protein accretion remains to be established. We aimed to fill this gap by including 33 healthy, older men (73 ± 2 yr) who were randomly assigned to ingest 10, 20, or 35 g of intrinsically l-[1-13C]phenylalanine-labeled whey protein ( n = 11/treatment). Ingestion of labeled whey protein was combined with continuous intravenous l-[ ring-2H5]phenylalanine and l-[ ring-2H2]tyrosine infusion to assess the metabolic fate of whey protein-derived amino acids. Dietary protein digestion and absorption rapidly increased following ingestion of 10, 20, and 35 g whey protein, with the lowest and highest (peak) values observed following 10 and 35 g, respectively ( P < 0.05). Whole body net protein balance was positive in all groups (19 ± 1, 37 ± 2, and 58 ± 2 μmol/kg), with the lowest and highest values observed following ingestion of 10 and 35 g, respectively ( P < 0.05). Postprandial muscle protein accretion, assessed by l-[1-13C]phenylalanine incorporation in muscle protein, was higher following ingestion of 35 g when compared with 10 ( P < 0.01) or 20 ( P < 0.05) g. We conclude that ingestion of 35 g whey protein results in greater amino acid absorption and subsequent stimulation of de novo muscle protein synthesis compared with the ingestion of 10 or 20 g whey protein in healthy, older men.

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Section: Discussionmentioning

confidence: 99%

Amino acid absorption and subsequent muscle protein accretion following graded intakes of whey protein in elderly men

Pennings

Groen

Lange³

et al. 2012

American Journal of Physiology-Endocrinology and Metabolism

284

228

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“…Complex interactions between myogenic, neural and hormonal mechanisms determine the rate 244 of gastric emptying and are associated with meal volume and content (Low, 1990 (Wright et al, 1998). However, when using non-disintegrating radio-opaque 254 pellets faster gastric emptying was observed in suckling piglets (PND21) compared to recently 255 weaned piglets (Snoeck et al, 2004).…”

Section: Gastrointestinal Transit 243mentioning

confidence: 99%

A review on early gut maturation and colonization in pigs, including biological and dietary factors affecting gut homeostasis

Everaert

Cruchten

Weström

et al. 2017

Animal Feed Science and Technology

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General rightsThis document is made available in accordance with publisher policies. Please cite only the published version using the reference above. Corresponding author: Nadia Everaert nadia.everaert@ulg.ac.be multiple components of the mucosal immune system. Furthermore, the composition of the 37 intestinal microbial communities seems to be affected by the early postnatal environment, which 38 might also contribute to gut maturation, metabolic and immune development. Understanding 39 the interplay between morphological, functional and immunological maturation, as influenced 40 by early microbial colonization and ingestion of dietary factors, is of utmost importance to 41 identify management and feeding strategies to optimize intestinal health. We discuss some 42 possible implications related to intrauterine growth restriction, and preterm delivery as these 43

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“…Viscosity induces changes in the rheological properties of digestive contents. This, in turn, can result in a reduced gastric emptying rate, although this is controversed for the solid phase [18], modified transit and motility in the small intestine [6], and reduced movement of nutrients from the lumen to the mucosal epithelium [12]. All these effects can result in slower or reduced intestinal absorption.…”

Section: Glucose Absorption Balance Across the Small Intestinementioning

confidence: 99%

Non-starch polysaccharides extracted from seaweed can modulate intestinal absorption of glucose and insulin response in the pig

Vaugelade¹,

Hoebler²,

Bernard³

et al. 2000

Reprod. Nutr. Dev.

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-We have investigated the possible effects of algal polysaccharides on postprandial blood glucose and insulin responses in an animal model, the pig. Three seaweed fibres of different viscosities, extracted from Palmaria palmata (PP), Eucheuma cottonii (EC), or Laminaria digitata (LD), were compared to purified cellulose (CEL). Blood glucose and plasma insulin levels were monitored and intestinal absorption quantified for 8 h following a high carbohydrate test-meal supplemented with 5% fibre. Digestive contents were also sampled, 5 h postprandial. As compared to CEL, PP had no effect on glucose and insulin responses. The latter decreased with EC, but glucose absorption balance was not modified. LD addition resulted in a dramatically reduced glucose absorption balance, accompanied by a higher amount of starch left in the small intestine. Among polysaccharides tested, only the highly viscous alginates could affect intestinal absorption of glucose and insulin response. seaweed / non-starch polysaccharides / intestinal absorption / glucoseRésumé -Les fibres alimentaires extraites d'algues peuvent moduler l'absorption intestinale du glucose et la réponse insulinique chez le porc. L'effet des fibres algales sur la réponse glycémique et insulinique a été étudié chez un modèle animal, le porc. Des fibres de viscosité différente, extraites de Palmaria palmata (PP), Eucheuma cottonii (EC), ou Laminaria digitata (LD), ont été comparées à de la cellulose purifiée (CEL). La glycémie et l'insulinémie plasmatique, ainsi que l'absorption intestinale du glucose ont été suivies 8 h après un repas-test hyperglucidique additionné de 5 % de fibres. Des contenus digestifs ont aussi été prélevés 5 h après le repas. L'addition de PP n'a pas modifié les réponses glycémique et insulinique par rapport à CEL. Elles étaient diminuées par l'addition Reprod. Nutr. Dev. 40 (2000) 33-47 33

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Nutritional Regulation of Gastric Secretion, Digestion and Emptying

Cited by 86 publications

References 132 publications

Amino acid absorption and subsequent muscle protein accretion following graded intakes of whey protein in elderly men

Amino acid absorption and subsequent muscle protein accretion following graded intakes of whey protein in elderly men

A review on early gut maturation and colonization in pigs, including biological and dietary factors affecting gut homeostasis

Non-starch polysaccharides extracted from seaweed can modulate intestinal absorption of glucose and insulin response in the pig

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