Nutritional status and severity of coronary artery disease

Abstract

Objective The aim of this study is to evaluate the association between Nutritional Risk Index (NRI), a simple tool to assess nutritional status, and coronary artery disease severity and complexity in patients undergoing coronary angiography. Methods This study is a retrospective analysis of 822 patients undergoing coronary angiography. Patients with previous revascularization were excluded. Gensini and SYNTAX scores were calculated according to the angiographic images to determine atherosclerosis severity. NRI was calculated as follows: NRI = [15.19 × serum albumin (g/dl)] + [41.7 × (body weight/ideal body weight)]. In patients ≥65 years of age, Geriatric NRI (GNRI) was used instead of NRI. GNRI was calculated as follows: GNRI = [14.89 × serum albumin (g/dl)] + [41.7 × (body weight/ideal body weight)]. Patients were then divided into three groups as previously reported: NRI < 92, NRI 92–98 and NRI > 98. Gensini and SYNTAX scores were compared between three groups. Results The mean age of study population was 61.9 ± 11.1 years. NRI < 92, 92–98, and >98 was measured in 212, 321 and 289 patients, respectively. There was no difference regarding to sex, BMI, smoking, hypertension and diabetes mellitus between three groups. Patients with NRI < 92 had the highest mean Gensini score than the patients with NRI 92–98 and NRI > 98 (38.0 ± 40.6 vs. 31.17 ± 42.4 vs. 25.8 ± 38.4, P = 0.005). Also patients with NRI < 92 had the highest mean SYNTAX score than the patients with NRI 92–98 and NRI > 98 (11.8 ± 12.9 vs. 9.3 ± 12.4 vs. 7.7 ± 11.8, P = 0.001). Also, Gensini score of ≥20 and high SYNTAX score of ≥33 were associated with lower NRI (P < 0.001 and P < 0.001, respectively). Conclusion In our study, nutritional status evaluated by the NRI was associated with more extensive and complex coronary atherosclerosis in patients undergoing coronary angiography.

Visceral Adiposity in Relation to Body Adiposity and Nutritional Status in Elderly Patients with Stable Coronary Artery Disease

“…Studies show that obese and malnourished patients have worse outcomes in comparison to their counterparts without malnutrition [ 38 , 39 ]. More importantly, nutritional status is linked to more extensive and complex coronary atherosclerosis in patients undergoing coronary angiography [ 15 ]. More importantly, there is evidence suggesting that nutritional status has a prognostic impact on CAD patients.…”

“…Studies indicate that the nutritional status evaluated is linked to more extensive and complex coronary atherosclerosis in patients undergoing coronary angiography and is significantly associated with long-term cardiovascular outcomes in patients with stable CAD. Therefore, assessing nutritional status may be useful for the risk stratification of CAD patients [ 15 , 16 , 17 ].…”

Nutritional Status of Coronary Artery Disease Patients—Preliminary Results

“…Similarly, a higher calcification score was also observed in patients with higher ECF in patients with chronic kidney disease, while in the presented study such a relationship was not present [ 35 ]. Nutritional status assessed with the nutritional risk index, which is based on laboratory parameters was also correlated to CAD advancement assessed with SYNTAX scale [ 36 ].…”