Nutritional status of allogeneic hematopoietic stem cell transplantation recipients: influencing risk factors and impact on survival

Abstract

Allogeneic HSCT patients having high comorbidity index, developing prolonged fever, and experiencing ≥grade II acute GI GVHD suffer from worsening in their nutritional status during hospitalization and after discharge. Also, nutritional status at admission and day 180 significantly influences their survival.

Nutritional Status and Quality of Life in Hospitalised Cancer Patients Who Develop Intestinal Failure and Require Parenteral Nutrition: An Observational Study

“…The PG-SGA identified 100.0% (24/24) of patients as being at risk of malnutrition and 70.8% (17/24) as having severe malnutrition, the majority of which were gastrointestinal and haematological cancer patients on active oncological treatment. Prevalence from studies with similar groups of patients ranged between 45.1% and 80.4% [ 38 , 39 , 40 , 41 ]. Results differed when the NST was used, as 80.0% (20/25) of patients were at risk, for whom close monitoring was required.…”

Assessing nutritional status in cancer

“…Numerous studies have shown the association between PG-SGA scores and specific nutritional parameters, for example weight loss, BMI, skinfold measures and hand grip strength [6]. Both earlier and recent data have demonstrated the PG-SGA's ability to predict clinical outcomes, for example survival, postoperative complications, length of stay, quality of life and hospitalization costs (Table 1) [9][10][11][12][13]. The PG-SGA is sensitive to changes in nutritional status over time, for example in response to nutritional interventions [14].…”

Stan odżywienia chorych po transplantacji komórek krwiotwórczych

“…W badaniu El-Ghammaz i wsp. [19] oceniono stan odżywienia 50 pacjentów po allogenicznym HCT (allo-HCT) za pomocą skali PG-S-GA (Patient Generated-Subjective Global Assessment) w momencie przyjęcia do szpitala, a następnie w 30. oraz w 180. dniu po HCT. Przy przyjęciu tylko dwóch pacjentów (4%) było niedożywionych.…”

“…Jednym z głównych celów oceny stanu odżywienia u chorych poddanych HCT jest identyfikacja osób zagrożonych niedożywieniem bądź niedożywionych [19]. Obniżenie masy ciała rozwija się stopniowo, osiągając swoje maksimum po około 40 dniach od przyjęcia do szpitala.…”