Nutritional support for the infant with extrahepatic biliary atresia

Kaufman, Stuart S.; Murray, Nancy D.; Wood, Robert; Shaw, Byers W.; Vanderhoof, Jon A.

doi:10.1016/s0022-3476(87)80002-1

Cited by 106 publications

(39 citation statements)

References 55 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…A facilidade de acesso e a disponibilidade de tabelas específicas para a idade fazem das medidas antropométricas um ótimo instrumento de vigilância para o suporte nutricional desses pacientes 3,4 .…”

Section: Resultsunclassified

“…Diversas causas explicam o comprometimento nutricional das crianças portadoras de doença hepática crôni-ca [3][4][5] :…”

Section: Introductionunclassified

“…Diversos índices clínicos são disponíveis para esse fim. Apesar das críticas existentes 3 , eles são úteis para caracterizar aspectos da composição corpórea e intensidade de acometimento nutricional. Além disso, constituem método prático para ser utilizado no seguimento ambulatorial de pacientes com doenças crônicas.…”

Section: Introductionunclassified

See 2 more Smart Citations

Nutritional evaluation of children with cholestatic diseases

Cardoso¹,

Porta²,

Vieira³

1997

J Pediatr (Rio J)

View full text Add to dashboard Cite

Objetivo: Caracterizar o grau de desnutrição e a utilidade dos índices antropométricos em crianças com doença crônica do fígado.Métodos: Foram examinados 11 pacientes, com idades variando de 5 a 105 meses. A definição do estado nutricional se fez através da determinação dos escores Z de peso para a idade (P/I) e estatura para a idade (E/I). Também se avaliou o estado nutricional através do critério de Waterlow: comparação do peso do paciente com o peso ideal para a estatura (P*), e estatura do paciente em relação à estatura ideal para a idade (E*). A estimativa dos depósitos de gordura foi feita através da medida da prega cutânea tricipital (PCT), e aquela do teor protéico do organismo, através da circunferência muscular do braço (CMB). A avaliação da ingestão alimentar, tanto qualitativa como quantitativamente, foi feita pelo método do recordatório de 24 horas.Resultados: Os escores Z médios de peso/idade (-1,18) e de estatura/idade (-1,26) foram inferiores a um desvio padrão da média, enquanto o escore Z médio de peso /estatura (0.8) situou-se numa faixa normal. A avaliação pelo método de Waterlow mostra uma média normal de P* e um pouco abaixo do normal de E*. Apenas 3 pacientes tinham medida de PCT maior que o percentil 15, e 5 deles tinham as medidas de CMB maior que esse mesmo percentil. A ingestão alimentar do ponto de vista qualitativo foi adequada em apenas 4 dos pacientes. Quanto à distribuição calórica dos nutrientes, em todos ela foi inadequada.Conclusões: A determinação dos escores Z permite caracterizar esse grupo de pacientes como desnutridos crônicos, com uma média de escore Z de P/E dentro da faixa do normal. O diagnóstico nutricional feito através do método de Waterlow aponta para a necessidade de se ter cautela na sua interpretação, uma vez que esses pacientes geralmente têm visceromegalia. O escore Z médio da prega cutânea tricipital foi o parâmetro que melhor refletiu o comprometimento nutricional dos pacientes. Do ponto de vista alimentar, considerando-se o fator de risco da patologia, tanto qualitativa como quantitativamente, a ingestão mostrou-se inadequada. J. pediatr. (Rio J.). 1997; 73(1):43-50:antropometria, avaliação nutricional, doença crônica do fígado, colestase. AbstractObjective: To characterize the type of malnutrition and to determine the usefulness of anthropometric indices in children with chronic liver disease (CLD) Methods: 11 children (aged 5 -105 mo) with CLD underwent anthropometric evaluation when they were clinically stable. The nutritional evaluation was made by the determination of Weight/ Age (W/A), Height/Age (H/A) and Weight/Height (W/E) Z scores. The nutritional evaluation by Waterlow's method was also made. The fat and protein body deposits were estimated by triceps skinfold and midarm muscular circumference measurements. The analysis of the 24-hour recall was used to evaluate the quality and pattern of the feeding. Results:The mean weight / age (W/A = -1.18) and height / age (H/A = -1.26) Z scores were depressed under 1 SD, whereas mean weight / height (W/H) Z...

show abstract

Section: Resultsunclassified

“…Diversas causas explicam o comprometimento nutricional das crianças portadoras de doença hepática crôni-ca [3][4][5] :…”

Section: Introductionunclassified

See 1 more Smart Citation

Nutritional evaluation of children with cholestatic diseases

Cardoso¹,

Porta²,

Vieira³

1997

J Pediatr (Rio J)

View full text Add to dashboard Cite

show abstract

“…1 Severe proteinenergy malnutrition affects approximately 60% of children with chronic liver disease, [2][3][4][5] being secondary to the interaction of multiple factors, including reduced nutritional intake, intestinal malabsorption and increased nutrient requirements due to increased energy expenditure. 1,6,7 Despite the knowledge that an adequate nutritional status contributes towards successful liver transplantation and lower rates of postoperative complications, 5,[8][9][10][11][12] studies performed during transplant pre-op show that a large proportion of patients with chronic liver disease exhibit inadequate nutrient intake and protein-energy malnutrition. 6,12 Another common manifestation of chronic liver disease is anemia.…”

Section: Introductionmentioning

confidence: 99%

Estado nutricional e absorção intestinal de ferro em crianças com doença hepática crônica com e sem colestase

Mattar¹,

Azevedo²,

Speridião³

et al. 2005

J. Pediatr. (Rio J.)

View full text Add to dashboard Cite

show abstract

“…Infants with EHBA with poor biliary drainage after portoenterostomy have significant malabsorption of fat and fat-soluble vitamins because of intraluminal bile acid deficiency (4,5). Apparently as a consequence, rickets occur in 59% of affected infants with unoperated EHBA (6).…”

mentioning

confidence: 99%

Bone Disease in Chronic Childhood Cholestasis II. Better Absorption of 25-OH Vitamin D than Vitamin D in Extrahepatic Biliary Atresia

1990

View full text Add to dashboard Cite

ABSTRACT. Infants with extrahepatic biliary atresia (EHBA) commonly develop rickets in infancy, whereas long-term survivors with EHBA commonly develop osteopenia with increasing age. We evaluated baseline vitamin D (Dz and D3), 25-OH vitamin D2 and D,, 1,25(0H)2 vitamin D, bone mineral content, and vitamin D2 and 25-OH vitamin D3 absorption in six infants and children (age 4-22 mo) with EHBA whose portoenterostomy failed to produce bile flow (group 1) and five infants and children (age 10112 to 8-4/12 y) with EHBA whose portoenterostomy repair led to good postoperative bile flow (group 2). Baseline serum vitamin Dz and DJ were undetectable in all subjects in group 1 despite supplements of 2500-5000 IU/ day, whereas all group 2 subjects given supplements (doses 400-5000 IU/d) had measurable levels. Baseline serum 25-OH vitamin D was less than 15 ng/mL in five of six (three with rickets) in group 1, whereas only one in group 2 had concentrations less than 15 ng/mL. A significantly blunted rise of vitamin D2 above baseline and reduced area under the absorption curve after 1000 IU/kg vitamin DZ were found in group 1 patients compared to group 2 (both p < 0.01), and five pediatric controls (both p < 0.01). The peak change and area under the absorption curve for serum 25-OH vitamin D3 from baseline after 10 pg/kg 25-OH vitamin D3 were significantly reduced for group 1 (both at least p < 0.05) and group 2 compared to controls (both p < 0.05). Malabsorption of supplemental doses of vitamin D compromises their efficacy to prevent rickets in infants with EHBA with poor bile flow after portoenterostomy. Despite severe malabsorption of vitamin D, we suggest that oral 25-OH vitamin D may be absorbed sufficiently to prevent rickets. (Pediatr Res 27:26-31, 1990) Abbreviations EHBA, extrahepatic biliary atresia PTH, parathyroid hormone EHBA accounts for approximately 25% of cases of neonatal cholestasis (1). Operable forms with atresia limited to the distal portions of the biliary tract account for 10-15% of the cases. In

show abstract

Nutritional support for the infant with extrahepatic biliary atresia

Cited by 106 publications

References 55 publications

Nutritional evaluation of children with cholestatic diseases

Nutritional evaluation of children with cholestatic diseases

Estado nutricional e absorção intestinal de ferro em crianças com doença hepática crônica com e sem colestase

Bone Disease in Chronic Childhood Cholestasis II. Better Absorption of 25-OH Vitamin D than Vitamin D in Extrahepatic Biliary Atresia

Contact Info

Product

Resources

About