O impacto da osteoporose no Brasil: dados regionais das fraturas em homens e mulheres adultos - The Brazilian Osteoporosis Study (BRAZOS)

Abstract

Objectives: The BRAZOS (The Brazilian Osteoporosis Study) study is the first epidemiological and population-based study carried out in a representative sample of Brazilian men and women, 40 years or older, with the objective of identifying the prevalence and main clinical risk factors (CRF) associated with low-impact fractures. This report shows the main results according to each region of the country. Patients and Methods: A total of 2,420 subjects (70% women) from 150 different cities in five geographic regions in Brazil, and from all different socio-economical classes were included in this study. Anthropometrical data, as well life style, previous fractures, nutritional status, physical activity, falls, and quality of life were evaluated by a quantitative individual survey. Low-impact fracture was defined as that resulting from a fall no greater than standing height of an individual. A P < 0.05 was considered significant. Results: Statistically significant differences in the prevalence of fractures among the five Brazilian regions according to gender or social class were not observed. However, in women, a higher incidence of fractures was observed in metropolitan areas than in rural areas, and a tendency for a higher frequency of fractures was observed in men from Northeastern states. Statistically significant differences among men from metropolitan areas or rural areas were not observed. Conclusions: Significant differences in the prevalence of low-impact fractures among the five different regions of Brazil were not observed, as well as its frequency or relevance of risk factors.

Epidemiology of Femur Fractures in the Elderly and Cost to the State of Paraná, Brazil

“…Women are more likely to develop osteoporosis and, consequently, fractures as observed in the BRAZOS study. 2 Caucasian was the prevalent ethnicity, which was not demonstrated in the national BRAZOS study. 2 We should consider that the population of Paraná is mostly Caucasian, which can cause a bias in the results, the same being observed in Pelotas, Rio Grande do Sul.…”

“…2 Caucasian was the prevalent ethnicity, which was not demonstrated in the national BRAZOS study. 2 We should consider that the population of Paraná is mostly Caucasian, which can cause a bias in the results, the same being observed in Pelotas, Rio Grande do Sul. 12 Femoral fracture is a condition of high mortality during hospitalization and months and years following the fracture.…”

“…The BRAZOS study showed that 70% of women and 85% of men with previous history of low-impact fracture were unaware of the diagnosis of osteoporosis. 2 The most populous eastern region concentrated the majority of the hospitalizations, with the capital, Curitiba, having most of the cases, probably due to better structure and the presence of the Workers' Hospital, which is a reference center for trauma. The total standardized incidence rate (≥ 60 years) was higher in females and increased progressively with increasing age similar to that in other epidemiological studies.…”

“…Osteoporotic fractures are usually related to falls and have known risk factors such as advanced age, female gender, early menopause, sedentary lifestyle, among others. 2 The incidence of fracture increases with age and maintains a higher proportion in females. 3 Citation: Oliveira CC, Borba VZC.…”

Osteoporose e Expectativa de Vida Saudável: estimativas para o Brasil em 2008

“…A maior prevalência da osteoporose no sexo feminino tem como consequência maior ocorrência de quedas 15 . A relação dessa enfermidade com quedas e fraturas são fatores determinantes na capacidade funcional e qualidade de vida dos indivíduos, além de acarretar altos custos decorrentes de seu tratamento e da perda de capacidade produtiva do indivíduo 15,39 . Como mencionado anteriormente, ainda são escassos os estudos sobre a prevalência de osteoporose na população brasileira e o VIGITEL do ano de 2008 apresenta uma oportunidade única e interessante de trabalhar com essa informação.…”