O índice BODE correlaciona-se com a qualidade de vida em pacientes com DPOC?

Abstract

Objective: To determine whether the Body mass index, airway Obstruction, Dyspnea, and Exercise capacity (BODE) index correlates with health-related quality of life in patients with COPD. Methods: We evaluated 42 patients with COPD, quantifying the following: lung function parameters; anthropometric variables; exercise capacity, with the six-minute walk test; dyspnea, with the modified Medical Research Council (MRC) scale; the BODE index; and quality of life, with the modified Saint George's Respiratory Questionnaire (mSGRQ). Patients were divided into two groups by disease severity: FEV 1 ≥ 50% and FEV 1 < 50%. Results: The mean BODE index was 2.58 ± 1.17 and 4.15 ± 1.81, respectively, for the FEV 1 ≥ 50% and FEV 1 < 50% groups. There was a significant difference between the groups in terms of FEV 1 and the FEV 1 /FVC ratio. There were moderate to significant correlations between the BODE index scores and all of the mSGRQ domains in the group of patients with FEV 1 <50%. Conclusions: The BODE index score correlated with the scores of all of the mSGRQ domains in COPD patients with FEV 1 < 50%. Therefore, COPD patients with FEV 1 < 50% die sooner and have a poorer quality of life.

Airway disease: similarities and differences between asthma, COPD and bronchiectasis

“…Characteristically, these individuals present with dyspnea and effort limitations due to the fixed airflow obstruction (75)-(77). More advanced stages of the disease result in a worse quality of life for these patients.…”

A survey of recently published cardiovascular, hematological and pneumological original articles in the Brazilian scientific press

“…Age and dyspnea are determinants of HS in both genders. Araujo and Holanda91 determined whether Body mass index, airway Obstruction, Dyspnea, and Exercise capacity (BODE) index correlates with health-related quality of life in patients with COPD. and found that the BODE index score correlated with the scores of all of the mSGRQ domains in COPD patients with FEV(1) <50%.…”

Functional outcomes in patients with chronic obstructive pulmonary disease: a multivariate analysis

“…The correlation between this score and FEV 1 was weak although statistically significant (r=-0.19, p=0.02). Similarly, Araujo and Holanda 11 did not detect a significant difference between the SGRQ psychosocial impact scores of two groups of COPD patients with FEV 1 ≥50% predicted and FEV 1 <50% predicted. The study of Verhage et al 15 found no significant correlation between FEV 1 and a variable designated "satisfaction in social relationships", and they did not find any significant differences between patients with GOLD stages II and III with regard to this factor.…”

“…The SGRQ psychosocial impact score indicates the aspects related to social and psychological disorders secondary to the disease 21 . Some studies have investigated outcomes related to the psychosocial impact of COPD 11 , 15 , 39 , 42 - 45 . In the present study, the linear regression models to explain this variable did not identify FEV 1 as a significant contributing factor, which corroborates the results of Huijsmans et al 39 .…”

“…According to the Statement on Pulmonary Rehabilitation, published by the American Thoracic Society and the European Respiratory Society, the isolated evaluation of only FEV 1 does not represent the complex clinical consequences of COPD 10 . Recently, a study was published showing earlier mortality and worse health-related quality of life (HRQOL) in patients with severe or very severe COPD 11 . However, several authors have debated and considered inadequate the use of FEV 1 as the unique parameter for evaluating and categorizing patients with COPD 4 , 12 - 16 .…”