I approach a set of processes that involve transformations, transpositions, and intermediations between different expressive forms of Amazonian Indigenous Peoples associated with the use of ayahuasca. I focus on groups of the Pano linguistic stock, particularly the Huni Kuin (Kaxinawa) and the example of the MAHKU (Movimento dos Artistas Huni Kuin), a new artistic collective created by some of these Indigenous People. I point to the complex meanings of the various expressive forms of these peoples, from traditional (oral narratives, graphics, visionary images linked to shamanic practices) to more recently adopted (figurative drawing and graphic recording in book format). I emphasize the importance of ayahuasca for the elaboration of these different expressive forms. By highlighting the meanings that imply the use of ayahuasca in certain Indigenous contexts, I also intend to contribute to the expansion of understanding of and broader debate about psychedelic experiences.