Oberflächenreaktionen “nach Bedarf”: elektrochemische Steuerung von Reaktionen an selbstorganisierten Monoschichten

Abstract

Kontrollierter Ablauf: Elektrochemisch induzierte Reaktionen an selbstorganisierten Monoschichten bieten Möglichkeiten für die ortsselektive Funktionalisierung von Oberflächen. Eine aktuelle Studie zeigt, wie mithilfe von Klick‐Reaktionen und durch elektrochemische Steuerung der Katalysatoraktivität ortsselektive Umsetzungen an einer Mikroelektrode möglich sind.

Electrochemically Driven, Electrode‐Addressable Formation of Functionalized Polydopamine Films for Neural Interfaces

“…[3] In particular, nerve cells are a representative example for electrically excitable cells, the functions of which are achieved by the tightly polarized electrical communications between neurons, and multielectrodes have been the core part of neuron-material interfaces. The differently functionalized electrodes on a substrate also could be utilized to investigate the responses of neurons at the single-cell level at a time.Electrochemically driven reactions on self-assembled monolayers have been used for electrode-selective functionalizations, [7] but this approach requires a specific electrode material, depending on the self-assembling molecules, and cumbersome synthetic procedures. [5] Although this coating approach has been successful in collective studies of neuronal connectivity and activities, [6] it would be desirable for sophisticated control and manipulation of neurons to develop methods for coating and functionalizing each electrode independently.…”

“…Electrochemically driven reactions on self-assembled monolayers have been used for electrode-selective functionalizations, [7] but this approach requires a specific electrode material, depending on the self-assembling molecules, and cumbersome synthetic procedures. As an alternative, conducting polymers have been adopted for coating of neural electrodes.…”

“…The electrode addressability would allow us to locate or manipulate neurons or synapses with directionality control, because the electrodes are asymmetrically functionalized, not to mention being beneficial in multiplexed detection of targets. The differently functionalized electrodes on a substrate also could be utilized to investigate the responses of neurons at the single-cell level at a time.Electrochemically driven reactions on self-assembled monolayers have been used for electrode-selective functionalizations, [7] but this approach requires a specific electrode material, depending on the self-assembling molecules, and cumbersome synthetic procedures. As an alternative, conducting polymers have been adopted for coating of neural electrodes.…”