Obesity and diabetes: dual epidemics on the rise

Wang, Jing; Armour, Tanya; Geiss, Linda S.; Engelgau, Michael M.

doi:10.1097/01.med.0000157075.71572.c3

Cited by 11 publications

(5 citation statements)

References 44 publications

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“…The worldwide epidemic of diabetes that have emerged with the dawning of the 21st century has shown to be a major public heath problem, having struck developed countries as well as those still developing [ 1 ]. The diabetes induced by streptozotocin has been a largely used in animal models to study diabetic-induced cardiovascular and autonomic dysfunction [ 5 , 18 - 20 ].…”

Section: Discussionmentioning

confidence: 99%

“…Diabetes is a great public health problem associated with high morbidity and mortality. Frequently, this condition is accompanied by other disorders, such as coronary heart disease, hypertension, dyslipidemia and obesity [ 1 ]. One consequence of this metabolic condition is the reduced exercise capacity that has been commonly observed in diabetic patients.…”

Section: Introductionmentioning

confidence: 99%

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Maximal exercise test is a useful method for physical capacity and oxygen consumption determination in streptozotocin-diabetic rats

Rodrigues

Figueroa

Mostarda

et al. 2007

Cardiovasc Diabetol

150

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Maximal exercise test is a useful method for physical capacity and oxygen consumption determination in streptozotocin-diabetic rats

Rodrigues

Figueroa

Mostarda

et al. 2007

Cardiovasc Diabetol

150

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“…Nearly 65% of US adults are overweight, >30% are obese and the prevalence of obesity is on the rise (1). Non‐Hispanic blacks are disproportionately affected, with black women suffering the highest rates of obesity (∼50%) overall (2).…”

Section: Introductionmentioning

confidence: 99%

Effect of Glycemic Load on Peptide‐YY Levels in a Biracial Sample of Obese and Normal Weight Women

Brownley

Heymen

Hinderliter

et al. 2010

Obesity

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Black women suffer a disproportionately higher rate of obesity than their white counterparts. Reasons for this racial disparity may reflect underlying differences in the appetite suppressing peptide-YY (PYY). The PYY response to food is differentially influenced by macronutrient content but the effect of glycemic load on PYY response is unknown. This study examined whether glycemic load influences fasting and postprandial PYY levels and whether fasting and postprandial PYY levels are lower in obese black women compared to normal weight black women and to white women. Data were collected from 40 women (20 black, 20 white; 10 each normal weight vs. obese) at the University of North Carolina Clinical and Translational Research Center (CTRC). Participants completed in counterbalanced order two 4½-day weight-maintenance, mixed macronutrient high vs. low glycemic load diets followed by a test meal of identical composition. Total PYY levels were assessed before and after each test meal. Results show no differences in fasting PYY levels but significantly less postprandial PYY area under the curve (PYYAUC) in the group of obese black women compared to each other group (race × obesity interaction, P < 0.04). PYYAUC was positively related to insulin sensitivity (P < 0.004) but was not affected by glycemic load (main and interactive effects, P > 0.27). These findings indicate that postprandial PYY secretion is not affected by glycemic load but is blunted in obese black women compared with normal weight black women and with white women; additionally, they begin to address whether blunted PYY secretion contributes uniquely to the pathogenesis of obesity in black women.

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“…La diabetes mellitus (DM), especialmente la tipo 2, afecta al 5,9% de la población adulta del mundo, con un predominio de casi 80% del total en los países en vías de desarrollo (1) .La incidencia de DM continúa creciendo a un ritmo sin precedentes de 171 millones en el 2004 a 366 millones para el estimado en el 2030 (2) . Es imperativo tomar medidas en la mejora de la atención de los pacientes, crear ambientes saludables y cambios sociales que los lleven a tener una mejor calidad de vida (3) .…”

Section: Introductionunclassified

Quality of life in patients with type 2 diabetes mellitus

Brítez

Taboada

2017

Rev. Nac. (Itauguá)

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RESUMENIntroducción: la calidad de vida relacionada con la salud (CVRS) se centra en los aspectos relativos a la percepción de la salud experimentada y declarada por la persona, en diferentes dimensiones tales como física, mental, social, la percepción general de la salud y la satisfacción alcanzada medida en diferentes niveles.Objetivo: determinar la CVRS de los pacientes con diabetes mellitus tipo 2 que son atendidos en el Dpto. de Medicina Interna del Hospital Nacional (Itauguá, Paraguay) en 2016.Metodología: el instrumento medición utilizado fue el cuestionario Diabetes-39 que es una escala multidimensional, que es completada por el propio paciente. A mayor puntuación, peor CVRS.Resultados: fueron encuestados 101 diabéticos. La edad media fue 57±16 años (rango 29-93 años). Hubo 55 varones (54%) y 46 mujeres (46%). El estado civil predominante fue el de casado (64%) y hubo predomino de sujetos con escolaridad secundaria (47%). La media de CVRS fue 57, valor que se encuentra por encima del estándar establecido por el cuestionario.El 49% de la muestra presenta mala CVRS en contraste con 51% con buena CVRS. Los dominios más afectados por orden de puntuación fueron: energía y Dentro de las variables estudiadas, el sexo masculino se constituyó en factor relacionado a la buena CVRS.Conclusiones: 49% de la muestra presenta mala CVRS y 51% buena CVRS.Palabras claves: diabetes mellitus tipo 2, calidad de vida relacionada con la salud, cuestionarios. Methodology:The instrument used as measurement was the Diabetes-39 questionnaire which is a multidimensional scale, which is completed by the patient. The higher the score, the worse HRQL.Results: 101 diabetics were surveyed. The mean age was 57 ± 16 years (range 29-93 years). There were 55 males (54%) and 46 females (46%). The predominant marital status was married (64%) and there were predominant subjects with secondary schooling (47%). The mean HRQoL was 57, a value that is above the standard established by the questionnaire. 49% of samples presented poor HRQL compared to 51% with good HRQL. The domains most affected by ranking order were: energy and mobility (60), anxiety-worriesome (62) and sexual functioning (66).Among the variables studied, the male sex was a factor related to good HRQoL.Conclusions: 49% of the sample had poor HRQL and 51% had good HRQL.Key words: diabetes mellitus type 2, quality of life related to health, quest.

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Obesity and diabetes: dual epidemics on the rise

Cited by 11 publications

References 44 publications

Maximal exercise test is a useful method for physical capacity and oxygen consumption determination in streptozotocin-diabetic rats

Maximal exercise test is a useful method for physical capacity and oxygen consumption determination in streptozotocin-diabetic rats

Effect of Glycemic Load on Peptide‐YY Levels in a Biracial Sample of Obese and Normal Weight Women

Quality of life in patients with type 2 diabetes mellitus

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