Obesity and lipid profiles in middle aged men and women in Tanzania

Njelekela, Marina; Negishi, Hiroko; Nara, Yasuo; Sato, Takeshi; Tomohiro, Masayuki; Kuga, Sachiko; Noguchi, Takanori; Kanda, Tomo; Yamori, Masashi; Mashalla, Yohana; Liu, L. Jian; Ikeda, Katsumi; Mtabaji, Jacob; Yamori, Yukio

doi:10.4314/eamj.v79i2.8901

Cited by 39 publications

(40 citation statements)

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“…Other areas such as Tehran and USA, similarly high prevalence of dyslipidemia was also observed 88.9% and 97% respectively [17,18]. The fairly high prevalence in this study may be attributed to the current trend towards urbanization and adoption to the western diet and lifestyle which was also reported by Njelekela et al [13]. This study showed a high prevalence of dyslipidemia with the commonest lipid abnormality being elevated LDL-C (64%)…”

Section: Discussionsupporting

confidence: 70%

“…In Tanzania, the prevalence of diabetic dyslipidemia was 95% in 2007 [12]. This is mainly due to the adopted western diet, sedentary lifestyle as well as physical inactivity resulting to obesity [13]. By determining the prevalence of abnormal lipid profile levels among the diabetic patients, it will provide the need to aggressively manage dyslipidemia among diabetic patients.…”

Section: Introductionmentioning

confidence: 99%

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Lipid Profile of Type 2 Diabetic Patients at a Tertiary Hospital in Tanzania: Cross Sectional Study

Shao¹

2017

JED

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Section: Discussionsupporting

confidence: 70%

Section: Introductionmentioning

confidence: 99%

Lipid Profile of Type 2 Diabetic Patients at a Tertiary Hospital in Tanzania: Cross Sectional Study

Shao¹

2017

JED

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“…The details of the study design have been described in our previous publication (8). In summary, the study was a cross sectional epidemiological survey to investigate the relationship between dietary factors and blood pressure.…”

Section: Methodsmentioning

confidence: 99%

“…After a 5-10 minutes rest, blood pressure (BP) was measured three times for each subject and the mean value was used in this analysis. In order to remove observer bias, we used an automated BP measurement system (KW machine) (8).…”

Section: Methodsmentioning

confidence: 99%

Determinants of hyperleptinaemia in an African population

et al. 2004

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Objective: To examine the determinants for elevated plasma leptin concentration in normal weight (NW), obese (OB), and morbidly obese (MO) individuals in Tanzania. Design: Cross-sectional epidemiological study, the CARDIAC study. Setting: Three areas in Tanzania; Dar es Salaam, urban(U), Handeni, rural(R) and Monduli, pastoralists(P), in August 1998. Subjects: Five hundred and forty five participants from a random sample of 600 people aged 46-58 years. Main outcome measures: Plasma leptin concentrations, height, weight, body mass index (BMI), lipid profiles, haemoglobin Alc (HBA1c), and blood pressure (BP).Results: Plasma leptin concentrations were higher in women than in men (women; 16.0 ng/ mL, men; 3.1 ng/mL; p<0.0001). Women showed a higher mean body mass index (BMI), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C) than men. In both genders, plasma leptin concentration, total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), triglycerides (TG), systolic BP (SBP) and diastolic BP (DBP) were significantly higher in OB than in NW participants. MO women had significantly higher leptin concentration, SBP and DBP compared with the other two groups. In NW men, log leptin concentrations showed a direct correlation with weight, BMI, HBAlc, TC, LDL-C, TG, SBP and DBP (all p<0.0001 except TG; p<0.001), while among NW women and OB men, weight and BMI correlated positively with log leptin (all p<0.05). OB women observed a positive correlation between log leptin and weight, BMI and LDL-C. Regression analysis indicated that among NW subjects, gender, BMI and TC explained 53.9% of the variation in log leptin. In OB subjects, gender, BMI and LDL-C explained 51.7% of the variability in leptin levels. No relationship was found between log leptin and CVD risk factors among MO subjects.

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“…The elevated consumption of trans fats, refined sugars, refined flours and preservatives, and low intake of dietary fibre and vital micronutrients, as a result of these new foods, has resulted in adverse health effects in the urban East African population 108,[130][131][132] . Recent evidence from the urban centre of Dar es Salaam in Tanzania revealed a positive relationship between the consumption of a Westernised (globalised) diet and the prevalence of NCDs, including risk factors which comprise the metabolic syndrome 108,[133][134][135][136][137] . The urban East African population is constantly confronted with the widespread availability of packaged food products 32,118,119,138 .…”

Section: Consequences Of Urbanisationmentioning

confidence: 99%