Obesity is a global epidemic, and researchers have been examining its prevalence and impact for decades [1]. In 2016, The World Health Organization (WHO) estimated that more than 1.9 billion adults over the age of 18 were overweight, and 650 million of these adults were obese [2]. Worldwide obesity in adults has greatly increased in the last~40 years [2]; a systematic review of over 1700 research studies found that the global proportion of overweight/obese adults increased from 28.8% to 36.9% in males, and 29.8% to 38% in females between 1980 and 2013 [1]. Furthermore, global obesity rates are projected to continue to steadily increase [3].Unfortunately, the epidemic of obesity is not limited to adults; children and adolescents are overweight and obese at alarming levels worldwide, with many countries reporting prevalence rates of 20-35% [4][5][6][7][8][9][10][11]. As seen in adults, the proportion of overweight/obese youth continues to rise [1,12]. Even more concerning is that obesity is becoming a prevalent issue in very young children; the WHO estimates that as of 2016, 41 million children under the age of five are overweight or obese [2]. In one a study of over 2000 four-year-old children from Spain, the prevalence of obesity increased from 5.4% to 10.1% over a two-year follow-up [4]. Obesity during childhood/adolescence drastically increases the probability of obesity in adulthood [13,14]. Early-onset obesity is setting children up for a lifelong risk of obesity-associated complications, as it is now understood that early markers of adult cardiovascular disease begin in childhood [15].Obesity is associated with disorders of almost every system in the body [16]. For example, adults with obesity have increased incidence of cardiovascular disease, diabetes, high cholesterol, and hypertension [17][18][19]. Childhood obesity is also associated with hypertension, insulin resistance, and liver disease, among others [16]. In a large cohort study of over 8500 nine-year-old Irish children, a staggering 11.1% of the population reported having a chronic illness that impaired daily living [20]. Children who reported living with chronic diseases were more often overweight or obese (32% prevalence) [20]. The negative health effects associated with obesity are not limited to physical outcomes; cognitive function is also decreased in obese children [21,22]. For example, a recent study examined the association of adiposity with achievement and cognitive function in obese children aged 7-9 years old vs. normal-weight children [23]. Compared to normal-weight children, children who were obese had lower performance on tests of reading and math. In the obese children, higher visceral adipose tissue was associated with poorer intellectual abilities and cognitive performance [23]. Published data indicate that an increasing number of children are at risk of