Obesity

Dietz, William H.

doi:10.1080/07315724.1989.10737966

Cited by 10 publications

(4 citation statements)

References 89 publications

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“…Today, obesity is a growing public health issue worldwide, with an increased risk for chronic and aggressive conditions such as respiratory complications, hypertension, diabetes mellitus, cardiovascular diseases, and cancer [ 1 – 3 ]. The increasing prevalence of overweight and obesity is seen in all age groups [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

RETRACTED ARTICLE: The best drug supplement for obesity treatment: a systematic review and network meta-analysis

Salari

Jafari

Darvishi

et al. 2021

Diabetol Metab Syndr

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Background Obesity is a complex disease with an increasing prevalence worldwide. There are different weight-management options for obesity treatment, including dietary control, exercise, surgery, and medication. Medications are always associated with different responses from different people. More safety and efficacy of drugs with fewer side effects are valuable for any clinical condition. In this systematic review and network meta-analysis, different anti-obesity drugs are compared to identify the most effective drug. Methods All relevant studies were extracted by searching national and international databases of SID, MagIran, ProQuest, PubMed, Science Direct, Scopus, Web of Science (WoS), and Google Scholar without time limit until October 2020. Finally, the meta-analysis was performed with the 11 remaining studies containing 14 different drug supplements. The standardized mean difference (SMD) was calculated at a 95% confidence interval (CI) to evaluate the effects of each treatment group compared with placebo. A random-effect model was used to evaluate the effect of individual studies on the final result. Heterogeneity and incompatibility of the network were assessed by Cochran’s Q and Higgins I2, and the Net Heat chart, respectively. Data analysis was performed using R software. Results Our results showed that there were significant mean effects in people intervened with Phentermine 15.0 mg + Topiramate 92.0 mg, Phentermine 7.5 mg + Topiramate 46.0 mg, Pramlintide, Naltrexone + Bupropion 32, and Liraglutide, with SMD effects size = − 9.1, − 7.4, − 6.5, − 5.9, − 5.35, respectively. Conclusion This study was performed to compare the effect of different drugs used for weight loss in obese patients. The most effective drugs for weight loss were phentermine and topiramate, pramlintide, naltrexone, bupropion, and liraglutide compared to placebo treatment, respectively. This study provides new insights into anti-obesity drugs and hopes to shed new light on future research to manage and treat obesity.

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Section: Introductionmentioning

confidence: 99%

RETRACTED ARTICLE: The best drug supplement for obesity treatment: a systematic review and network meta-analysis

Salari

Jafari

Darvishi

et al. 2021

Diabetol Metab Syndr

View full text Add to dashboard Cite

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“…However, there was a significant difference between the estimated weight (M = 146.55) and the actual measured weight (M = 155.74), t = 2.99, p< .006. On whether they thought they were overweight (3), about right (2), or underweight (1), high BMis (M = 2.50) thought they were significantly heavier than low BMI' s (M = 2.08), t = 2.25, p< .05.…”

Section: Resultsmentioning

confidence: 99%

Being Overweight: Negative Outcomes for African American Adolescents

Setiloane

2004

Nutr Health

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The present study looked at how bodyweight affected African American adolescents their physical characteristics of height and weight, their behavioral characteristics of eating preferences, and their psychological characteristics of self-esteem and locus of control. In the summer of 2002 29 African-American adolescents who were participating in a one month Summer Institute were questioned on the perceptions of their weight and their food practices. They also completed self-esteem and locus of control scales. The Self-esteem scales used were the Rosenberg Self-Esteem scale (RSE), the Rosenberg-Simmons Self-Esteem scale (RSSE), the Rosenberg Depressive Affect scale (RDA), and the Rosenberg Self-Consciousness scale (RSC) The subjects had their height and weight measured and their calculated Body Mass Index (BMI) was divided into high BMI's (124 and above) and low BMI's (123 and below). High BMI's thought they were significantly heavier than low BMI's (p = 0.5), and drank more soft drinks (p = 0.1) than low BMI's. Further, the high BMI group had significantly lower self-esteem than the low BMI group on the RSE scale (p = 0.03) and the RSSE scale (p = 0.02).

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“…There are plausible biological mechanisms that may explain the relationships between high BMI or weight and OC failure. First, higher body weight is associated with increased basal metabolic rate, [15][16][17] which may shorten the duration of action of oral contraceptives. Second, drugs (such as OCs) that undergo phase II hepatic metabolism have shown increased clearance in obesity, 18,19 perhaps through induction of hepatic enzymes.…”

Section: Discussionmentioning

confidence: 99%