Obesity, salivary glands and oral pathology

Roa, Ignacio; Sol, Mariano del

doi:10.25100/cm.v49i4.3919

Cited by 39 publications

(36 citation statements)

References 71 publications

(174 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Nevertheless, not only tooth decay is a negative consequence of obesity. Chronic gingivitis or periodontitis is one of the most prevalent diseases of an inflammatory-destructive background and, similarly to obesity, it is classified as a social disease [ 18 ]. We found benign gingivitis in both the study and control groups, as shown by the GI and SBI.…”

Section: Discussionmentioning

confidence: 99%

Poor Oral Hygiene and High Levels of Inflammatory Cytokines in Saliva Predict the Risk of Overweight and Obesity

Nijakowski

Lehmann

Rutkowski

et al. 2020

IJERPH

View full text Add to dashboard Cite

The study aimed to determine if oral hygiene influences not only oral health but also potentially metabolic disorders such as overweight or obesity. Participants were 94 patients: 40 with increased body mass and 54 with normal body mass. The methods included dental examination, a questionnaire concerning hygienic habits and an assessment of selected salivary inflammatory markers. The new parameter named “cleaning index” (describing the interaction between average time of tooth brushing in minutes and its frequency per day) significantly correlated with Body Mass Index (RSpearman = 0.300). The multivariate regression model incorporating cleaning index, approximal plaque index, receptor 1 for tumor necrosis factor-alpha (TNFα-R1) and interleukin-15 (IL-15) had a high power to predict overweight or obesity (AUC = 0.894). Patients with poor oral hygiene (approximal plaque index >40%) were more than eight times more likely to suffer from obesity than patients with good oral hygiene. Cleaning index higher than 4 decreased the odds by about 85%. Oral hygiene habits, adjusted by salivary concentrations of selected inflammatory markers may allow predicting effectively overweight or obesity risk. Early proper dental prophylaxis and treatment could lead to the better prevention of metabolic disorders.

show abstract

Section: Discussionmentioning

confidence: 99%

Poor Oral Hygiene and High Levels of Inflammatory Cytokines in Saliva Predict the Risk of Overweight and Obesity

Nijakowski

Lehmann

Rutkowski

et al. 2020

IJERPH

View full text Add to dashboard Cite

show abstract

“…Obesity and oral health may share similar causal and behavioral mechanisms (8), mainly related to the diet. Previous studies reported an association between obesity and several oral diseases, such as dental caries (9), periodontal disease, tooth loss (7,10,11), and xerostomia (defined as the subjective perception of oral dryness) (9,12).…”

Section: Introductionmentioning

confidence: 99%

Oral Health and Nutritional Characteristics of Adults With Morbid Obesity: A Multivariate Analysis

et al. 2020

View full text Add to dashboard Cite

The relationship between oral health and nutritional aspects are complex, especially in individuals with chronic diseases and comorbidities, such as morbid obesity. Thus, the aim of the present study was to identify oral health and nutritional-related patterns in 113 individuals, aged 19–68 years (92 females), seeking treatment for morbid obesity. Sociodemographic variables and medical records were examined, in addition to the consumption of fruit, vegetables, candies, and processed foods. Measures of body mass index, neck, waist and hip, caries experience (DMFT index), Community Periodontal Index (CPI index), and salivary physicochemical aspects were gathered. Aspects of oral health-related quality of life and symptoms of dry mouth were evaluated by means of Oral Health Impact Profile (OHIP-14) and Xerostomia Inventory-XI questionnaires. K-means cluster analysis and, subsequently, comparisons between clusters (one-way ANOVA) were performed (α = 5%). Three clusters were generated: Cluster 1 (labeled “Young”; n = 77) was characterized by younger participants with higher BMI, who reported the use of distractors while eating, the smallest number of meals/day, and who consumed sweetened drinks and processed food the day before. Cluster 2 (labeled “Diabetic individuals”; n = 12) was characterized by older participants with the highest proportion of diabetic participants (100% were diabetic; 73% insulin users), lower BMI, higher DMFT index and OHIP-14 and xerostomia scores, and who reported having consumed fruit and vegetables the day before. Finally, Cluster 3 (labeled “Poor periodontal health”; n = 24) was characterized by participants with the worse periodontal condition (higher CPI), and lower salivary flow, pH, and buffer capacity. Cluster 1 and 2 were the groups that showed higher demand for nutritional and dietetic counseling, because of the poor eating behavior and higher serum glucose levels, respectively. On the other hand, Cluster 2 and 3 showed the higher demand for oral rehabilitation and dental treatment because of the loss of teeth and worse periodontal condition, respectively, besides the need for dietetic counseling. This sample of individuals with morbid obesity showed very unique oral-health and nutritional characteristics and special needs patterns that should be identified to adjust or change unhealthy habits, thus improving the assistance of this condition.

show abstract

“…The latter decreases during weight loss in obese subjects (Rasmusen et al, 1995), which indicates that type III collagen is most affected during obesity, as was found in the stroma of the parotid gland of our experimental model. Type III collagen is composed of immature fibrils, likely due to fibrogenesis or fibrosis of the gland (Karsdal, 2016), which could explain the functional changes in the salivary glands during obesity (Roa & del Sol, 2018).…”

Section: Discussionmentioning

confidence: 99%

Types I and III Parotid Collagen Variations and Serum Biochemical Parameters in Obese Rats Exposed to Monosodium Glutamate

Roa

Sol

2020

Int. J. Morphol.

Self Cite

View full text Add to dashboard Cite

show abstract

Obesity, salivary glands and oral pathology

Cited by 39 publications

References 71 publications

Poor Oral Hygiene and High Levels of Inflammatory Cytokines in Saliva Predict the Risk of Overweight and Obesity

Poor Oral Hygiene and High Levels of Inflammatory Cytokines in Saliva Predict the Risk of Overweight and Obesity

Oral Health and Nutritional Characteristics of Adults With Morbid Obesity: A Multivariate Analysis

Types I and III Parotid Collagen Variations and Serum Biochemical Parameters in Obese Rats Exposed to Monosodium Glutamate

Contact Info

Product

Resources

About