Objective Olfactory Outcomes after Revision Endoscopic Sinus Surgery

Hsu, Chao-Yuan; Wang, Ying‐Piao; Shen, Ping‐Hung; Weitzel, Erik K; Lai, Jen-Tsung; Wormald, Peter‐John

doi:10.2500/ajra.2013.27.3939

Cited by 34 publications

(55 citation statements)

References 40 publications

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“…Of all the included studies, improvement in olfaction after sinus surgery was described in all 24 publications, except for one . However, this was true for only certain subgroups in nine studies . The main distinguishing factor for a positive outcome in these studies was the presence of polyps, revision versus primary surgery, or anosmia versus hyposmia preoperatively.…”

Section: Resultsmentioning

confidence: 99%

“…After close evaluation of the publications, 24 studies reached the inclusion criteria for this review. These have been published over the last 20 years and used the USPIT or single components or the whole battery of the Sniffin’ Sticks test . Almost all the included studies were published in the period from 2007 to 2018; only one earlier study from 1994 was identified …”

Section: Resultsmentioning

confidence: 99%

“…One study used the Sniffin’ Sticks Threshold Test only . Six studies used the 40‐item UPSIT . Two studies used a combination of at least two (sub‐) tests (I and T), and seven trials used the whole TDI‐score of the Sniffin' Sticks Set …”

Section: Resultsmentioning

confidence: 99%

“…Of the 11 studies that described the grouped results of CRSwNP and CRSsNP, only four saw an improvement in olfaction in both groups, whereas seven reported an improvement only in the CRSwNP group . Two studies did not analyze the polyp subgroups …”

Section: Resultsmentioning

confidence: 99%

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Recovery of olfaction after sinus surgery for chronic rhinosinusitis: A review

Haxel

2019

The Laryngoscope

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Objective Investigation of the postoperative olfactory function after sinus surgery for chronic rhinosinusitis (CRS) with and without polyps in a review. Data Sources PubMed. Review Methods A comprehensive literature search was conducted through June 2018 using relevant keywords. The titles/abstracts were reviewed to identify studies evaluating the sense of smell in CRS‐patients pre‐ and postoperatively by either using the whole or parts of the University of Pennsylvania Smell Identification Test or the Sniffin’ Sticks test. Study characteristics and outcome data of the included studies were extracted. Results In total, 106 studies were retrieved. Twenty‐four studies comprising 1,956 patients were included after quality assessment. The number of patients investigated per study was 19 to 206. In the 24 studies, 959 patients with nasal polyps and 516 without nasal polyps were described. The follow‐up times varied between 0.5 and 28 months. Twenty‐three studies reported an improved sense of smell, at least in certain subgroups. An overall improvement was seen in approximately 50% of the included patients. Nasal polyposis and preoperative anosmia were associated with a higher chance of improvement in olfaction. In those studies that commented on deterioration after sinus surgery, a decrease in olfaction was found in a range from 0% to 10% of cases. Conclusion Olfaction can be improved by sinus surgery in about every second patient, especially if the patient had chronic rhinosinusitis with polyps, was anosmic, and had no prior surgery. A deterioration of sense of smell after surgery is rare. Laryngoscope, 129:1053–1059, 2019

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

Recovery of olfaction after sinus surgery for chronic rhinosinusitis: A review

Haxel

2019

The Laryngoscope

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“…The only significant prognostic factor that seems consistent across several studies is that patients with CRSwNP have a better chance for improvement in smell compared with those patients with CRSsNP. 12,36,37 Removing polyps alleviates obstruction, improves nasal airflow, and allows odorant molecules a better chance to reach the olfactory receptors.…”

Section: Impact Of Endoscopic Sinus Surgery On Olfaction In Chronic Rmentioning

confidence: 99%

Olfaction in Endoscopic Sinus and Skull Base Surgery

Thompson

Kern

Conley

2015

Otolaryngologic Clinics of North America

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Longitudinal improvement and stability of olfactory function in the evaluation of surgical management for chronic rhinosinusitis

Levy

Mace

Sansoni

et al. 2016

Int Forum Allergy Rhinol

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BACKGROUND Abnormal olfaction is common with chronic rhinosinusitis (CRS) and associates with various measures of sinonasal inflammation. The Brief Smell Identification Test (BSIT) has demonstrated improvements in abnormal olfactory detection following endoscopic sinus surgery (ESS), but olfaction remains understudied using this instrument. Discerning longitudinal, postoperative durability in olfaction is critical for patient counseling. METHODS Adult participants with medically recalcitrant CRS were prospectively enrolled into a multi-institutional cohort study and observed for 18-months following ESS. Olfaction was operationalized using BSIT scores collected at baseline, 6-months, 12-months, and 18-months postoperatively and compared using repeated measures ANOVA. RESULTS 122 participants met inclusion criteria and were recruited between March, 2011 and February, 2014. Improvement in mean BSIT scores at 6-month follow-up were reported for all participants (p=0.014) with greatest improvement in subjects with nasal polyposis (p=0.001). No differences in mean BSIT scores were found between 6-month and 18-months overall, however subjects with comorbid asthma (F(2)=5.29; p=0.010) and nasal polyposis (F(2)=3.99; p=0.033) reported significant mean worsening. Prevalence of abnormal olfaction decreased from 28% preoperatively to 17% at 6-months (p=0.015), for all subjects, without significant change 12-months (19%; p=0.791) or 18-months (21%; p=0.581) postoperatively. CONCLUSIONS Postoperative improvement in olfaction was reported 6-months after ESS using BSIT scores, with greatest improvements in patients undergoing polypectomy. Overall improvement persisted between 6-month and 18-month following ESS for most patient subgroups, however, dysosmia worsened after initial improvement in patients with asthma and nasal polyps, highlighting the need for further identification of prognostic factors associated with abnormal olfaction in CRS.

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Objective Olfactory Outcomes after Revision Endoscopic Sinus Surgery

Abstract: RESS resulted in objective evidence of olfactory improvement in approximately one-half of our cohort over 16 months of follow-up and offers a treatment option for an otherwise poor prognosis condition.

Cited by 34 publications

References 40 publications

Recovery of olfaction after sinus surgery for chronic rhinosinusitis: A review

Recovery of olfaction after sinus surgery for chronic rhinosinusitis: A review

Olfaction in Endoscopic Sinus and Skull Base Surgery

Longitudinal improvement and stability of olfactory function in the evaluation of surgical management for chronic rhinosinusitis

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