Moderate-to-vigorous physical activity (MVPA) is essential for disease prevention and health promotion. Emerging evidence suggests other intensities of physical activity (PA), including light-intensity activity (LPA), may also be important, but there has been no rigorous evaluation of the evidence. The purpose of this systematic review was to examine the relationships between objectively measured PA (total and all intensities) and health indicators in school-aged children and youth. Online databases were searched for peer-reviewed studies that met the a priori inclusion criteria: population (apparently healthy, aged 5-17 years), intervention/exposure/comparator (volumes, durations, frequencies, intensities, and patterns of objectively measured PA), and outcome (body composition, cardiometabolic biomarkers, physical fitness, behavioural conduct/pro-social behaviour, cognition/academic achievement, quality of life/well-being, harms, bone health, motor skill development, psychological distress, self-esteem). Heterogeneity among studies precluded meta-analyses; narrative synthesis was conducted. A total of 162 studies were included (204 171 participants from 31 countries). Overall, total PA was favourably associated with physical, psychological/social, and cognitive health indicators. Relationships were more consistent and robust for higher (e.g., MVPA) versus lower (e.g., LPA) intensity PA. All patterns of activity (sporadic, bouts, continuous) provided benefit. LPA was favourably associated with cardiometabolic biomarkers; data were scarce for other outcomes. These findings continue to support the importance of at least 60 min/day of MVPA for disease prevention and health promotion in children and youth, but also highlight the potential benefits of LPA and total PA. All intensities of PA should be considered in future work aimed at better elucidating the health benefits of PA in children and youth.Key words: physical activity, body composition, cardiometabolic biomarkers, fitness, behavioural conduct, bone health, academic achievement, quality of life, well-being, children.Résumé : L'activité physique d'intensité moyenne à vigoureuse (« MVPA ») est essentielle à la prévention des maladies et à la promotion de la santé. D'après de récentes données, l'activité physique (« PA ») pratiquée à d'autres intensités telles que légères (« LPA ») s'avère aussi importante, mais il n'y a pas d'évaluation rigoureuse de ces faits. Cette analyse documentaire systématique a pour objectif d'examiner la relation entre l'activité physique mesurée objectivement (totale et à chacune des intensités) et des indicateurs de la santé chez des enfants et des jeunes d'âge scolaire. On a cherché dans des bases de données en ligne pour identifier des études révisées par des pairs et présentant a priori les critères d'inclusion suivants : population (apparemment en santé, sujets âgés de 5 à 17 ans), intervention/exposition/comparateur (volume, durée, fréquence, intensité et types de mesure objective de PA) et le résultat (composition c...