Majorana zero modes (MZMs)-bearing potential applications for topological quantum computingare verified in quasi-one-dimensional (1D) Fermion systems, including semiconductor nanowires, magnetic atomic chains, planar Josephson junctions. However, the existence of multi-bands in these systems makes the MZMs fragile to the influence of disorder. Moreover, in practical perspective, the proximity induced superconductivity may be difficult and restricted for 1D systems. Here, we propose a flexible route to realize MZMs through 1D topological kink states by engineering a 2D electron gas with antidot lattices, in which both the aforementioned issues can be avoided owing to the robustness of kink states and the intrinsically attainable superconductivity in high-dimensional systems. The MZMs are verified to be quite robust against disorders and the bending of kink states, and can be conveniently tuned by varying the Rashba spin-orbit coupling strength. Our proposal provides an experimental feasible platform for MZMs with systematic manipulability and assembleability based on the present techniques in 2D electron gas system.