OBSERVATIONS ON <i>AXINELLA</i> SP. HEMAGGLUTININ

Gold, E. R.; Phelps, C. F.; Khalap, S.; Balding, P.

doi:10.1111/j.1749-6632.1974.tb53024.x

Cited by 32 publications

(14 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although a specific role for sponge lectins in cell adhesion and reaggregation has not been established, a brief discussion of them here seems appropriate since they may very well be involved in cell-cell interactions (MOller, 1982) and/or reactions to foreign materials in vivo. Gold et al (1974) partially characterized a low-molecular-weight protein (15-18,000) from Axinella sp., which agglutinates human red cells and is inhibited in its agglutination by D-galactose and other D-galactose containing saccharides (lacto-N-tetrose-f3-1,3; lactose; melibiose). Interestingly, this sponge lectin binds both calcium and iron and contains a high carboxylic acid content.…”

Section: Reaggregation Of a Hexactinellidmentioning

confidence: 99%

“…Interestingly, this sponge lectin binds both calcium and iron and contains a high carboxylic acid content. It also agglutinates other types of mammalian cells and it was suggested that it may act in vivo as a type of AF (Gold et al, 1974), although this now seems unlikely. The Axinella lectin prepared by MacLennan (1974) had a higher molecular weight (32,000), but this may be due to differences in preparative techniques, since Bretting (1979) has now shown that there are at least two galactose-specific Axinella lectins that can be purified.…”

Section: Reaggregation Of a Hexactinellidmentioning

confidence: 99%

See 1 more Smart Citation

The Cell Biology of Sponges

Simpson

1984

695

604

View full text Add to dashboard Cite

PrefaceThe writing of this work was stimulated by discussions with colleagues in the fields of biochemistry, developmental biology, and physiology who expressed their, and other's, need for a current, critical review and analysis of sponge cell biology, and secondly by my own conviction that the field of sponge biology in general could benefit from such a synthesis and evaluation of the data. The major problem faced in writing this book was that of balancing the text relative to presenting, on the one hand, a review of the data and, on the other hand, a synthesis of it. A vigorous attempt has been made to be as uniform as possible in reviewing data but this, of course, is not always possible because some papers stand out as key advances in one or more areas. To the extent that it has been feasible to synthesize specific perspectives or to emphasize deficiencies in knowledge, these have been done. A major effort is made to review cellular structure per se since this has not previously been attempted. Some speculations are also to be found and these, hopefully, will not only stimulate new investigations but will also serve as respites from the unavoidable rigidity of data review. Much effort has been expended to avoid errors, although it is probably not possible in an undertaking of this scope to finally arrive at an error-free state. For such of those that do occur by omission or otherwise, I take full and sole responsibility.There are a number of important, recent monographs and symposial volumes which contain much information on sponge cell biology as well as other topics. Outstanding among them is Biologie des Spongiaires (C. Levi and N. Boury-Esnault, Eds., 1979. Editions de CNRS, Paris).

show abstract

Section: Reaggregation Of a Hexactinellidmentioning

confidence: 99%

Section: Reaggregation Of a Hexactinellidmentioning

confidence: 99%

The Cell Biology of Sponges

Simpson

1984

695

604

View full text Add to dashboard Cite

show abstract

“…A resurgence of interest in these factors has taken place recently, largely as a result of their implication as a part of a system for the recognition of foreign antigens (Boyden, 1966; Tripp, 1966;Cushing, 1967) and because of the unusual properties of plant lectins already mentioned. Recently natural hemagglutinins have been reported in numerous invertebrates including sponges (Gold, Phelps, Khalap and Balding, 1974), pelecypod mollusks (Jenkin and Rowley, 1970;Acton, Bennett, Evans and Schrohenloher, 1969;Cornick and Stewart, 1973), gastropod mollusks (Pemberton, 1970a;1970b;Bizot, 1971;Hammarstrom and Kabat, 1971;Matsubara and Boyd, 1974;Pauley, Granger and Krassner, 1971); annelids (Cooper, Lemmi and Moore, 1974); arthropods (Miller, Ballback, Pauley and Krassner, 1972;Marchalonis and Edelman, 1968;Finstad, Litman, Finstad and Good, 1972;Pauley, 1973;Scott, 1971;Anderson, Day and Good, 1972), and echinoderms (Finstad, Litman, Finstad and Good, 1972). Halocynthia hemagglutinin was assayed in hemolymph cleared of blood cells by centrifugation.…”

Section: Discussionmentioning

confidence: 99%

“…Hall and Rowlands (1974b) reported that trypsinized cells were not agglutinated more strongly by lobster agglutinins; however, increased titers for trypsin-treated red cells were found in the hemolymph of the sea urchin (Ryoyama, 1974) and the sponge (Gold, Phelps, Khalap and Balding, 1974). Incubation of red cells with either trypsin or pronase greatly increased their susceptibility to the hemagglutinin of H. pyriformis.…”

Section: Discussionmentioning

confidence: 99%

“…Limulin was purified and shown to be a glycoprotein of 13.9 S, 335,000 MW consisting of 19,000 MW subunits held together by noncovalent bonds. The hemagglutinin of the sponge can be inhibited by galactose (Gold, Phelps, Khalap and Balding, 1974). On this basis it was suggested that the limulin receptor is a complex carbohydrate containing sialic acid and N-acetylglucosamine and is not a monosaccharide.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation