Obstetrical and neonatal outcomes in women following gastric bypass: a Danish national cohort study

Abstract

Gastric bypass may reduce the risk of preeclampsia, emergency cesarean section, and perinatal asphyxia, compared with adipose women without surgery. Compared with normal weight controls women who had had a gastric bypass had a higher risk of hypertension, gestational diabetes, and acute abdominal pain during pregnancy and their children a lower birthweight and higher incidence of admittance to neonatal intensive care.

A meta‐analysis of maternal and fetal outcomes of pregnancy after bariatric surgery

“…The frequency of cesarean among women who had undergone BS varied between 15.4% [17] and 61.5% [20], compared with between 29.8% [14] and 65.8% [18] of obese women who have not undergone BS. The difference in frequency of cesarean between women who had and had not undergone BS was even bigger in Dell'Agnolo et al's study [37].…”

“…1). After exclusion of 10 studies (Supplementary Material S1), 11 [13][14][15][16][17][18][19][20][21][22][23] were included in the meta-analysis ( Table 1). The outcomes analyzed for each study are shown in Supplementary Material S2, along with the definitions used for each of the outcomes.…”

“…Nine articles that reported the maternal outcome of GDM in women with or without surgery [14][15][16][17][18][19][20]22,23] were included in the analysis of GDM, with 711 cases overall. The random effects model showed that GDM was significantly less likely among women who had undergone BS than among those who had not (pooled OR 0.31, 95% CI 0.15-0.65; I 2 = 85.2%, P b 0.001) ( Fig.…”

“…Six studies [14,15,17,19,22,23] were included in the analysis of postpartum hemorrhage, with 181 cases in a sample of 4655 participants. Postpartum hemorrhage was less likely among women who had undergone BS than among those who had not, but the difference was not significant (summary OR 0.62, 95% CI 0.38-1.00; I 2 = 8.7%, P = 0.361) (Fig.…”

“…Seven studies [14,15,[17][18][19][20]22] were included in the analysis of incidence of cesarean delivery. Cesarean was not significantly more likely among women who had undergone BS than among those who had not (summary OR 0.75, 95% CI 0.50-1.13; I 2 = 74.2%, P = 0.001) (Fig.…”