Obstructing Malignant Lesions of the Colon

Fitchett, Claiborne W.; Hoffman, George C.

doi:10.1016/s0039-6109(16)43992-7

Cited by 9 publications

(3 citation statements)

References 16 publications

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“…Other techniques that could ascertain the presence of the malignant obstruction include contrast enema or gentle endoscopic evaluation. 26,27 Furthermore, CT scan can garner information regarding the possibility of insertion of an endoscopic stent. 10,11 The site and length of the primary lesion and the severity of obstruction are important considerations.…”

Section: Discussionmentioning

confidence: 99%

Surgery for Obstructed Colorectal Malignancy in an Asian Population: Predictors of Morbidity and Comparison Between Left- and Right-Sided Cancers

Tan

Sim

2010

Journal of Gastrointestinal Surgery

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Section: Discussionmentioning

confidence: 99%

Surgery for Obstructed Colorectal Malignancy in an Asian Population: Predictors of Morbidity and Comparison Between Left- and Right-Sided Cancers

Tan

Sim

2010

Journal of Gastrointestinal Surgery

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“…Our patient rapidly developed liver metastases after surgery, except for emergency surgery [25] and absence of adjuvant chemotherapy, factors consisting of BRAF V600E mutation and MSS status may also contribute to the aggressiveness. Fortunately, the patient achieved an exciting efficacy of CR when 8 cycles of capecitabine were completed and obtained long-term survival, which was encouraging, as few patients using capecitabine alone had obtained such great efficacy, long-term survival were also rare.…”

Section: Discussionmentioning

confidence: 99%

Long-term survival of an elderly female with metastatic colon cancer after treated with capecitabine monotherapy

et al. 2019

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Rationale: Colorectal cancer (CRC) is one of the most common cancers all over the world, and approximately 70% of the newly diagnosed patients are over 65 years old. Due to the aging of society, there will be more and more elderly patients of CRC in the future. Treatment of CRC in elderly patients is much more challenging thanks to multiple factors including disabling comorbidities as well as declines in organs function, especially in advanced or metastatic settings. Patient concerns: An 82-year-old female without history of disease was admitted to the emergency room because of abdominal pain in December 2009. A computed tomography (CT) scan of the abdomen was performed immediately, which revealed bowel obstruction. Diagnoses: The histopathological examination of the resected specimen confirmed well-to-moderately differentiated colonic adenocarcinoma with a stage of IIIB (T3N1M0) based on the NCCN tumor-node-metastasis (TNM) classification system. Interventions: The patient underwent emergency surgery and rejected adjuvant chemotherapy, but was diagnosed with multiple liver metastases 3 months later. Then she received capecitabine monotherapy as first-line treatment. Outcomes: The efficacy achieved complete response (CR) when 8 cycles were completed and the agent was continued as maintenance treatment until totally 16 cycles were completed. Up to the latest follow-up, the disease remained CR and the progression-free survival (PFS) has achieved approximately 87 months. She is still alive and has good quality of life. Lessons: Capecitabine monotherapy may be an effective treatment in advanced or metastatic colorectal cancer (mCRC) for elderly patients.

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“…This has a lower operative mortality and morbidity than a staged procedure. This primary resection with anastomosis is certainly as safe as an ileotransverse colostomy[ 4 ].…”

Section: Discussionmentioning

confidence: 99%

Colonic carcinoma with multiple small bowel perforations mimicking intestinal obstruction

et al. 2006

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Obstructing Malignant Lesions of the Colon

Cited by 9 publications

References 16 publications

Surgery for Obstructed Colorectal Malignancy in an Asian Population: Predictors of Morbidity and Comparison Between Left- and Right-Sided Cancers

Surgery for Obstructed Colorectal Malignancy in an Asian Population: Predictors of Morbidity and Comparison Between Left- and Right-Sided Cancers

Long-term survival of an elderly female with metastatic colon cancer after treated with capecitabine monotherapy

Colonic carcinoma with multiple small bowel perforations mimicking intestinal obstruction

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