Obstructive jaundice secondary to pancreatic adenocarcinoma in a seven-year-old male

Smith, John Henry; Baugh, Clarence M.; Reppun, Thomas S.

doi:10.1016/s0022-3468(85)80300-6

Cited by 10 publications

(9 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This agrees with documentation in the literature [1][2][3][4][5][6][7][8][9] . Onyekwereet al 3 further stated that the pruritus is usually very distressing, thus necessitating their presentation in the hospital.…”

Section: Discussionsupporting

confidence: 91%

“…The high mortality rate recorded in our present study is in keeping with documentation in the literature [1][2][3][4][5][6][7][8][9][10][11][12] . Apart from the 4 patients (31%), who were lost to follow up, the rest died within 18months of diagnosis.…”

Section: Discussionsupporting

confidence: 91%

“…This was also our experience in this series. In our study, the average duration of symptoms before presentation was 9 weeks and this agrees with the late presentation observed by other workers around the world with its attendant poor prognosis [1][2][3][4][5][6][7][8][9] .The use of baseline investigations like urinalysis and liver function test in this condition cannot be over-emphasized as these when combined with clinical evaluation and abdominal ultrasound scan were most useful in making a diagnosis of this condition in our environment where diagnostic facilities are quite limited and expensive. At the earlier part of this study, abdominal CT Scan could only be done several kilometers away from our city at great cost.…”

Section: Discussionsupporting

confidence: 90%

“…It is common after the age of forty but has been reported in children. The prognosis is generally poor and palliative treatment is often the rule as late presentation often makes curative resection (Whipples procedure) impossible [1][2][3][4][5][6] .At the time of diagnosis, 52% of all patients have distant metastasis and 26% of them already have locoregional spread 1 . The relative one year survival of patients with this disease irrespective of stage is only 24% and the overall 5 year survival is 5%.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Presentation of Pancreatic Cancer in a Dedicated HepatoPancreato-Biliary Surgery Unit of a Tertiary Health Facility, South-South, Nigeria: A Four Year Prospective Study.

OENgim¹,

ADMarwa²,

MEkong³

et al. 2014

IOSRJDMS

View full text Add to dashboard Cite

Carcinoma of the pancreas is a common gastrointestinal neoplasm (July, 2008 -June, 2012.A total of fourteen patients were seen with this condition during the study period. There were more females than males with a ratio of 2.5:1. The age range was 40-80years with a mean age of 58yrs. The commonest mode of presentation was a combination of jaundice, pruritus and weight loss. The presence of jaundice with pruritus were the principal symptoms that brought these patients to the hospital. Late presentation is common in our environment and prognosis is poor.

show abstract

Section: Discussionsupporting

confidence: 91%

Section: Discussionsupporting

confidence: 91%

Section: Discussionsupporting

confidence: 90%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Presentation of Pancreatic Cancer in a Dedicated HepatoPancreato-Biliary Surgery Unit of a Tertiary Health Facility, South-South, Nigeria: A Four Year Prospective Study.

OENgim¹,

ADMarwa²,

MEkong³

et al. 2014

IOSRJDMS

View full text Add to dashboard Cite

show abstract

“…Obstructive jaundice in childhood encompasses a differential diagnosis that includes choledocholithiasis, pancreatitis, pancreatic pseudocyst, choledochal cyst, intrahepatic neoplasm, and pancreatic tumors [1]. Unlike adults, children rarely develop malignancy of the pancreas.…”

mentioning

confidence: 99%

Management of children with pancreatic head mass

Park

Dunn

Atkinson

2006

Journal of Pediatric Surgery

View full text Add to dashboard Cite

Rare ductal adenocarcinoma of the pancreas in patients younger than age 40 years

Lüttges

Stigge

Pacena

et al. 2003

Cancer

View full text Add to dashboard Cite

BACKGROUND Pancreatic ductal adenocarcinomas (PDACs) are extremely rare before age 40 years. The objective of the current study was to determine whether the features of PDACs in patients age < 40 years differ from those in older patients. The authors reviewed the literature and their own files. METHODS The cases reported in the literature were evaluated to determine their precise diagnoses and characteristic features. In a series of 439 PDACs from the authors' files, tumors in patients age < 40 years were identified, and their clinicopathologic features and certain genetic features were compared with those in a selected group of patients age > 40 years. RESULTS Of 71 pancreatic carcinomas reported in patients age < 40 years, only 20 fully qualified as PDACs. The remaining tumors represented malignancies other than PDACs, such as pancreatoblastoma, solid‐pseudopapillary neoplasms, acinar cell carcinomas, and endocrine tumors. PDACs in patients age < 20 years were the absolute exception and commonly were associated with risk factors such as Peutz–Jeghers syndrome, hereditary pancreatic cancer syndrome, and preceding radiotherapy. In the authors' series of patients, there were 6 PDACs and 4 PDAC variants in patients age < 40 years (0.2%), all in male patients. These tumors compared well with the PDACs in patients age > 40 years in their pathologic and molecular findings. Three patients were age ≤ 20 years, and 2 of those patients had a mucinous component with MUC2 positivity. CONCLUSIONS The incidence of PDACs in patients age < 40 years was approximately 0.3%, and the incidence in patients age < 20 years was 0.1%. Their clinicopathologic findings were comparable to those in patients age > 40 years, but they seemed to include more variants, particularly mucinous carcinomas. In addition, PDACs in younger patients frequently appeared to be associated with genetic factors. Cancer 2004;100:173–82. © 2003 American Cancer Society

show abstract

Obstructive jaundice secondary to pancreatic adenocarcinoma in a seven-year-old male

Cited by 10 publications

References 3 publications

Presentation of Pancreatic Cancer in a Dedicated HepatoPancreato-Biliary Surgery Unit of a Tertiary Health Facility, South-South, Nigeria: A Four Year Prospective Study.

Presentation of Pancreatic Cancer in a Dedicated HepatoPancreato-Biliary Surgery Unit of a Tertiary Health Facility, South-South, Nigeria: A Four Year Prospective Study.

Management of children with pancreatic head mass

Rare ductal adenocarcinoma of the pancreas in patients younger than age 40 years

Contact Info

Product

Resources

About