Obstructive metastatic malignant melanoma of the heart: Imminent pulmonary arterial occlusion caused by right ventricular metastasis with unknown origin of the primary tumor

Başarıcı, İbrahim; Demir, İbrahim; Yılmaz, Hüseyin; Altekin, Refik Emre

doi:10.1016/j.hrtlng.2005.11.001

Cited by 15 publications

(12 citation statements)

References 8 publications

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“…Malignant melanomas can be found in any part of the heart, most frequently in the right atrium, but they can also cause obstructive features of the right ventricular outflow tract,5 13 as in our case. A sequela to this particular location is pulmonary embolisation of both tumour and thrombotic fragments.…”

Section: Discussionmentioning

confidence: 49%

“…Metastatic spread to the heart is a frequent result in patients with malignant melanoma, accounting for >50% of cases at autopsy 1. Infiltration of the conduction system and coronary circulation by melanoma has been reported,2 3 but by far the most common presentation is involvement of the right side of the heart, often the right atrium and not uncommonly right ventricular outflow tract obstruction 1 4 5. Whether primary or metastatic, the prognosis for patients with cardiac melanoma is extremely poor, although there are rare reports describing at least intermediate term survival after surgery 6 7.…”

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confidence: 99%

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Massive cardiac invasion by amelanotic melanoma with obstructive clinical features

Dubrey

Grocott-Mason

Mittal

et al. 2008

Postgraduate Medical Journal

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Reports of malignant melanoma involving the heart usually describe metastatic spread of pigmented (melanotic) forms of this tumour. We describe, and illustrate, a patient presenting with features related to cardiac tamponade and intracardiac obstruction. Transthoracic echocardiography initially showed a large mass within the right ventricular outflow tract. The full extent of infiltration of this tumour was demonstrated by computed tomography scanning and the specific tumour type by immunohistochemical staining procedures. The case is unusual in relation to the extreme size of this amelanotic melanoma at presentation and the fact that it appears to be a solitary metastasis.

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Section: Discussionmentioning

confidence: 49%

mentioning

confidence: 99%

Massive cardiac invasion by amelanotic melanoma with obstructive clinical features

Dubrey

Grocott-Mason

Mittal

et al. 2008

Postgraduate Medical Journal

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“…A tumor's anatomic location and extent of invasion determine the feasibility of surgical intervention, which should optimally be performed during the early stages of the disease 6). A complete resection of an intracardiac melanoma prevents potential morbidities that are associated with progressive intracardiac growth, such as superior vena cava syndrome, right ventricular outflow and inflow obstruction, dysrhythmia, cardiac tamponade, and heart failure 6).…”

Section: Discussionmentioning

confidence: 99%

“…A complete resection of an intracardiac melanoma prevents potential morbidities that are associated with progressive intracardiac growth, such as superior vena cava syndrome, right ventricular outflow and inflow obstruction, dysrhythmia, cardiac tamponade, and heart failure 6). Even when total resection is not possible, conservative surgery can relieve symptoms and prevent imminent cardiac failure.…”

Section: Discussionmentioning

confidence: 99%

Malignant Melanoma of Unknown Primary Origin Presenting as Cardiac Metastasis

et al. 2012

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“…La mayoría de los casos de tumores cardiacos se descubren de modo fortuito en necropsias en los que la muerte ha tenido otro origen (incluso violenta) y, por lo tanto, no son atribuibles a esta patología [9][10][11] .…”

Section: Introductionunclassified

Muerte súbita por metástasis de melanoma en aurícula derecha: Revisión de los tumores cardiacos

2011

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ResumenLos tumores cardiacos son entidades clínicas muy raras, sin embargo tienen especial interés desde el punto de vista médico-forense porque pueden ser la causa de una muerte súbita. Presentamos el caso de un varón de 38 años de edad con un melanoma de coroides que fallece de forma súbita cuatro años después de realizarse el diagnóstico. La autopsia médico legal y el estudio histopatológico mostraron un tromboembolismo pulmonar originado sobre una metástasis de melanoma en la aurícula derecha. En el presente artículo llevamos a cabo una revisión general de los tumores cardiacos. Palabras clave: Tumores cardiacos. Muerte súbita. Metástasis melanoma. AbstractCardiac tumors are rare clinical entity, however, they have an especial interest in forensic medicine because they can be the source of sudden death. We report a case of a 38-years old male who had been diagnosed with primary choroidal melanoma some years before his sudden death. Forensic autopsy and histopathologic examination revealed pulmonary embolism due to a melanoma metastasis in the right atrium. In addition, in this article we conduct a general review of cardiac tumors.

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Obstructive metastatic malignant melanoma of the heart: Imminent pulmonary arterial occlusion caused by right ventricular metastasis with unknown origin of the primary tumor

Cited by 15 publications

References 8 publications

Massive cardiac invasion by amelanotic melanoma with obstructive clinical features

Massive cardiac invasion by amelanotic melanoma with obstructive clinical features

Malignant Melanoma of Unknown Primary Origin Presenting as Cardiac Metastasis

Muerte súbita por metástasis de melanoma en aurícula derecha: Revisión de los tumores cardiacos

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