Obstructive sleep apnea and risk of COVID-19 infection, hospitalization and respiratory failure

Kruif, Martijn D. de; Voncken, S F J; Laven, S A J S; Feron, T M H; Kolfoort-Otte, A A B

doi:10.1007/s11325-020-02271-2

Cited by 8 publications

(5 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The prevalence of hospitalized patients with OSA was higher than that of those without OSA [15.3 vs. 3.4%, p < 0.0001; odds ratio (OR) 5.20, 95% CI (4.43, 6.12)]. A similar result was found regarding respiratory failure rate [OR, 1.98; 95% CI (1.65, 2.37)] ( 15 ).…”

Section: Association Between Covid-19 and Osasupporting

confidence: 60%

A wearable device for at-home obstructive sleep apnea assessment: State-of-the-art and research challenges

Tran¹,

Nam²,

Tuan³

2023

Front. Neurol.

View full text Add to dashboard Cite

In the last 3 years, almost all medical resources have been reserved for the screening and treatment of patients with coronavirus disease (COVID-19). Due to a shortage of medical staff and equipment, diagnosing sleep disorders, such as obstructive sleep apnea (OSA), has become more difficult than ever. In addition to being diagnosed using polysomnography at a hospital, people seem to pay more attention to alternative at-home OSA detection solutions. This study aims to review state-of-the-art assessment techniques for out-of-center detection of the main characteristics of OSA, such as sleep, cardiovascular function, oxygen balance and consumption, sleep position, breathing effort, respiratory function, and audio, as well as recent progress in the implementation of data acquisition and processing and machine learning techniques that support early detection of severe OSA levels.

show abstract

Section: Association Between Covid-19 and Osasupporting

confidence: 60%

A wearable device for at-home obstructive sleep apnea assessment: State-of-the-art and research challenges

Tran¹,

Nam²,

Tuan³

2023

Front. Neurol.

View full text Add to dashboard Cite

show abstract

“…The prevalence of OSA in COVID-19 has been the subject of debate [ 10 ]. A previous study by Maas et al found a prevalence of 6.3% in patients with COVID-19 in their cohort from the USA [ 6 ].…”

Section: Discussionmentioning

confidence: 99%

“…However, it is important to note that most data in these studies were derived from large, multicenter databases [ 5 – 7 ]. Despite the advantages of large-scale databases to demonstrate associations, they are vulnerable to bias [ 10 , 11 ]. In order to confirm a meaningful relationship, more detailed studies in different settings are needed.…”

Section: Introductionmentioning

confidence: 99%

Impact of obstructive sleep apnea on clinical outcomes in patients hospitalized with COVID-19

et al. 2021

Self Cite

View full text Add to dashboard Cite

Purpose Data from large patient registry studies suggested an increased incidence and increased mortality in coronavirus disease-2019 (COVID-19) in patients with a history of obstructive sleep apnea (OSA). This study aimed to compare the prevalence of OSA in patients with and without COVID-19 among patients admitted to the same hospital in the same time period. In addition, the impact of OSA on clinical outcomes of COVID-19 infection was investigated. Methods Observational cohort study. Clinical data were collected retrospectively from the complete medical records for each patient individually from March 1st 2020 to May 16th 2020. Results A total of 723 patients were diagnosed with COVID-19 and 1161 with non-COVID-19 disease. The prevalence of OSA did not differ between these groups ( n = 49; 6.8% versus n = 66; 5.7%; p = 0.230). In patients with COVID-19, mortality was increased in the group of 49 patients with OSA ( n = 17; 34.7%) compared to 674 COVID-19 patients without OSA ( n = 143; 21.2%; p = 0.028). This increased risk of mortality in COVID-19 patients with OSA (OR = 2.590; 95%CI 1.218–5.507) was independent from Body Mass Index (BMI), male gender, age, diabetes, cardiovascular disease, and obstructive lung disease. Presence of OSA in COVID-19 disease was further associated with an increased length of hospital stay (12.6 ± 15.7 days versus 9.6 ± 9.9 days; p = 0.049). Conclusion The prevalence of OSA did not differ between patients with or without COVID-19, but mortality and hospital length of stay were increased in patients with OSA and comorbid COVID-19. Hence, OSA should be included in COVID-19 risk factor analyses, Clinicians should be aware of the association and the mechanism should be further explored.

show abstract

“… 41 This indicates the need for a differentiated approach to treatment in obese patients with OSAS affected by this coronavirus, as this population is more susceptible to respiratory failure and, consequently, more severe outcomes ( Figure 2 ). 55 , 56 …”

Section: Resultsmentioning

confidence: 99%

Molecular aspects of COVID-19 and its relationship with obesity and physical activity: a narrative review

et al. 2023

View full text Add to dashboard Cite

BACKGROUND: Severe acute respiratory syndrome coronavirus 2 has several mechanisms of action related to inflammatory responses, especially in individuals diagnosed with obesity. This hyperinflammatory clinical profile resulting from the association between obesity and coronavirus disease 2019 (COVID-19) may be attenuated by regular physical activity. OBJECTIVE: The aim of this study was to review the evidence on the consequences of physical inactivity and physical activity on COVID-19 in patients with obesity. DESIGN AND SETTING: Narrative review at the Bahiana School of Medicine and Public Health in Salvador, Brazil. METHODS: We searched evidence on the association of COVID-19 with physical activity and obesity using the following keywords: "covid-19, " "physical activity, " and "obesity". The databases used were MEDLINE (PubMed), ScienceDirect, and Virtual Health Library. Studies published from 2019 to 2021 and available in Portuguese, English, and Spanish were included. The final search was conducted on September 26, 2021. RESULTS: We identified 661 studies in the database, among which 71 were considered for inclusion in the narrative review of the molecular aspects of COVID-19 and its relationship with physical activity and obesity. CONCLUSION: This literature review enabled the perception of the relationship between the molecular mechanisms of COVID-19 and obesity. Regular physical activity had various benefits for the inflammatory condition of the studied population, highlighting moderate-intensity..

show abstract

Obstructive sleep apnea and risk of COVID-19 infection, hospitalization and respiratory failure

Cited by 8 publications

References 4 publications

A wearable device for at-home obstructive sleep apnea assessment: State-of-the-art and research challenges

A wearable device for at-home obstructive sleep apnea assessment: State-of-the-art and research challenges

Impact of obstructive sleep apnea on clinical outcomes in patients hospitalized with COVID-19

Molecular aspects of COVID-19 and its relationship with obesity and physical activity: a narrative review

Contact Info

Product

Resources

About