“…The results of this literature review correlate with other recent literature reviews and meta-analyses, all of which show a consistent association of OSA with increased risk of stroke independent of other SRFs (Das & Khan, 2012, Dong, Zhang, & Qin, 2013, Johnson & Johnson 2010, Loke, Brown, Kwok, Niruban, & Myint, 2012. The Sleep Heart Health Study was the largest epidemiological study, involving 5,422 diverse community-based participants prospectively followed for over 8 years, that revealed statistically strong evidence that OSA increases the risk of first-time stroke, specifically in men (Redline et al, 2010).…”